Palliative care utilization and racial and ethnic disparities among women with de novo metastatic breast cancer in the United States

• Published in: Breast cancer research and treatment Vol. 200; no. 3; pp. 347 - 354
• Main Authors: Giap, Fantine, Ma, Sung Jun, Oladeru, Oluwadamilola T., Hong, Young-Rock, Yu, Brian, Mailhot Vega, Raymond B., Brooks, Eric D., Singh, Anurag K., Okunieff, Paul G., Mendenhall, Nancy P., Bradley, Julie A.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2023; Springer; Springer Nature B.V
• Subjects: Analysis; Breast cancer; Breast Neoplasms - epidemiology; Breast Neoplasms - therapy; Cancer research; Ethnicity; Female; Health aspects; Healthcare Disparities; Hispanic American women; Hispanic or Latino; Hispanic people; Humans; Medical research; Medicine; Medicine & Public Health; Medicine, Experimental; Metastases; Metastasis; Minority & ethnic groups; Oncology; Original Laboratory Investigation; Pacific Islander people; Palliation; Palliative Care; Palliative treatment; Race; Retrospective Studies; United States - epidemiology; White people; Women; United States; Palliative care; Metastatic breast cancer; Health equity; Under-represented minorities
• ISSN: 0167-6806; 1573-7217
• DOI: 10.1007/s10549-023-06963-7

Purpose The potential disparities in palliative care delivery for underrepresented minorities with breast cancer are not well known. We sought to determine whether race and ethnicity impact the receipt of palliative care for patients with metastatic breast cancer (MBC). Methods We retrospectively reviewed the National Cancer Database for female patients diagnosed with stage IV breast cancer between 2010 and 2017 who received palliative care following diagnosis of MBC to assess the proportion of patients who received palliative care, including non–curative-intent local–regional or systemic therapy. Multivariable logistic regression analysis was performed to identify variables associated with receiving palliative care. Results 60,685 patients were diagnosed with de novo MBC. Of these, only 21.4% ( n  = 12,963) received a palliative care service. Overall, there was a positive trend in palliative care receipt from 18.2% in 2010 to 23.0% in 2017 ( P  < 0.001), which persisted when stratified by race and ethnicity. Relative to non-Hispanic White women, Asian/Pacific Islander women (aOR 0.80, 95% CI 0.71–0.90, P  < 0.001), Hispanic women (adjusted odds ratio [aOR] 0.69, 95% CI 0.63–0.76, P  < 0.001), and non-Hispanic Black women (aOR 0.94, 95% CI 0.88–0.99, P  = 0.03) were less likely to receive palliative care. Conclusions Fewer than 25% of women with MBC received palliative care between 2010 and 2017. While palliative care has significantly increased for all racial/ethnic groups, Hispanic White, Black, and Asian/Pacific Islander women with MBC still receive significantly less palliative care than non-Hispanic White women. Further research is needed to identify the socioeconomic and cultural barriers to palliative care utilization.