Study of tribological properties of human buccal epithelium cell membranes using probe microscopy
In this work demostrates a unique method for determining the absolute value of the friction force of a nanoobject on the surface of a cell membrane using atomic force microscopy. The tribological properties of membranes of adult human buccal epithelium cells in the presence of a protective adsorptio...
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Published in | Scientific reports Vol. 12; no. 1; p. 11302 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
04.07.2022
Nature Publishing Group Nature Portfolio |
Subjects | |
Online Access | Get full text |
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Summary: | In this work demostrates a unique method for determining the absolute value of the friction force of a nanoobject on the surface of a cell membrane using atomic force microscopy. The tribological properties of membranes of adult human buccal epithelium cells in the presence of a protective adsorption buffer layer of ~ 100 nm on their surface were studied using atomic force microscopy in the contact scanning mode. Local mapping of the tribological characteristics of the surface was carried out, viz. friction
F
L
=
F
L
(x, y)
and adhesion
F
adh
=
F
adh
(x, y)
forces were measured. Studies of the friction force
F
fr
on the membrane surface at the nanolevel showed that its value varies discretely with an interval equal to
l
LF
≈ 100 nm. It was shown that such discreteness is determined by the interval
l
LF
of the action of adhesive forces
F
adh
and indicates the fractal nature of the functional dependence of the friction force on the coordinate
F
fr
=
F
fr
(x)
. Thus, for nano-objects with dimensions ≤
l
LF
, the absolute value of
F
fr
decreases according to a power law with an increase in the size of the object, which contradicts the similar dependence of the friction force for macro-objects in the global approximation. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2045-2322 2045-2322 |
DOI: | 10.1038/s41598-022-14807-5 |