Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review

This review is an account of methods that use various strategies to control microfluidic flow control with high accuracy. The reviewed systems are divided into two large groups based on the way they create flow: passive systems (non-mechanical systems) and active (mechanical) systems. Each group is...

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Published inBiosensors (Basel) Vol. 12; no. 11; p. 956
Main Authors Iakovlev, Aleksei P., Erofeev, Alexander S., Gorelkin, Petr V.
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.11.2022
MDPI
Subjects
active pumping methods
Analysis
Biochips
Control systems
Efficiency
Flow control
Geometry
Gravity
Health aspects
Humans
lab-on-a-chip
Lab-On-A-Chip Devices
lab-on-a-disk
Mechanical systems
Methods
Microfluidic Analytical Techniques
Microfluidic devices
Microfluidics
Microfluidics - methods
Multitasking
passive pumping methods
Personal computers
point-of-care devices
Polymerization
Porous materials
Reagents
Review
Reynolds number
Smartphone
Viscosity
Russia
point-of-care devices
microfluidics
active pumping methods
lab-on-a-chip
passive pumping methods
lab-on-a-disk
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Summary:This review is an account of methods that use various strategies to control microfluidic flow control with high accuracy. The reviewed systems are divided into two large groups based on the way they create flow: passive systems (non-mechanical systems) and active (mechanical) systems. Each group is presented by a number of device fabrications. We try to explain the main principles of operation, and we list advantages and disadvantages of the presented systems. Mechanical systems are considered in more detail, as they are currently an area of increased interest due to their unique precision flow control and “multitasking”. These systems are often applied as mini-laboratories, working autonomously without any additional operations, provided by humans, which is very important under complicated conditions. We also reviewed the integration of autonomous microfluidic systems with a smartphone or single-board computer when all data are retrieved and processed without using a personal computer. In addition, we discuss future trends and possible solutions for further development of this area of technology.
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ISSN:2079-6374
2079-6374
DOI:10.3390/bios12110956