Validation of the Infectious Diseases Society of America's Diabetic Foot Infection Classification System

• Published in: Clinical infectious diseases Vol. 44; no. 4; pp. 562 - 565
• Main Authors: Lavery, Lawrence A., Armstrong, David G., Murdoch, Douglas P., Peters, Edgar J. G., Lipsky, Benjamin A.
• Format: Journal Article
• Language: English
• Published: Chicago, IL The University of Chicago Press 15.02.2007; University of Chicago Press; Oxford University Press
• Subjects: Age Distribution; Aged; Amputation; Amputation - statistics & numerical data; Associated diseases and complications; Bacterial Infections - classification; Bacterial Infections - epidemiology; Bacterial Infections - surgery; Biological and medical sciences; Brief Reports; Communicable Diseases; Diabetes; Diabetes complications; Diabetes mellitus; Diabetes. Impaired glucose tolerance; Diabetic angiopathies; Diabetic foot; Diabetic Foot - classification; Diabetic Foot - microbiology; Diabetic Foot - surgery; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Feet; Female; Foot diseases; Humans; Incidence; Infections; Infectious diseases; Longitudinal Studies; Lower extremity; Male; Medical sciences; Middle Aged; Orthopedic surgery; Probability; Prognosis; Prospective Studies; Risk Assessment; Risk factors; Sensitivity and Specificity; Sex Distribution; Societies, Medical; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Wound Infection - microbiology; America; Endocrinopathy; Infection; Skin disease; Nervous system diseases; Treatment; Surgical amputation; Diabetic Foot; Surgery; Diabetes mellitus; Disease of the foot; Classification
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1086/511036

In this longitudinal study of 1666 persons with diabetes, there was an observed trend toward an increased risk for amputation (χ2 test for trend, 108.0; P < .001), higher-level amputation (χ2 test for trend, 113.3; P < .001), and lower extremity—related hospitalization (χ2 test for trend, 118.6; P < .001) with increasing infection severity. The Infectious Diseases Society of America's foot infection classification system may be a useful tool for grading foot infections.