Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression

The gene nmrA of Aspergillus nidulans has been isolated and found to be a homolog of the Neurospora crassa gene nmr-1, involved in nitrogen metabolite repression. Deletion of nmrA results in partial derepression of activities subject to nitrogen repression similar to phenotypes observed for certain...

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Published in	Journal of Bacteriology Vol. 180; no. 7; pp. 1973 - 1977
Main Authors	Andrianopoulos, A. (University of Melbourne, Parkville, Victoria, Australia.), Kourambas, S, Sharp, J.A, Davis, M.A, Hynes, M.J
Format	Journal Article
Language	English
Published	United States American Society for Microbiology 01.04.1998
Series	Note
Subjects	ACIDE AMINE ALANINA ALANINE amino acid metabolism Amino Acid Sequence AMINO ACID SEQUENCES AMINO ACIDS AMINOACIDOS ASPERGILLUS NIDULANS Aspergillus nidulans - genetics Aspergillus nidulans - metabolism Bacteriology Base Sequence CHEMICAL COMPOSITION CLONACION CLONAGE CLONING Cloning, Molecular COMPOSICION QUIMICA COMPOSITION CHIMIQUE DELETIONS Eukaryotic Cells EXONS FACTEUR DE TRANSCRIPTION FACTORES DE TRANSCRIPCION FENOTIPOS Fungal Proteins Fungal Proteins - genetics GABA GAMMA-AMINOBUTYRIC ACID GENBANK/AF041976 GENE GENES Genes, Fungal GENETICA GENETICS GENETIQUE GLUTAMINA GLUTAMINE INTRONS metabolism METABOLISME DE L'AZOTE METABOLISME DES PROTEINES METABOLISMO DEL NITROGENO METABOLISMO PROTEICO Metabolites Microbiology MOLECULAR SEQUENCE DATA MUTANT MUTANTES MUTANTS NITRATE NITRATE REDUCTASE NITRATES NITRATO REDUCTASA NITRATOS Nitrogen NITROGEN METABOLISM NUCLEOTIDE SEQUENCE pharmacology PHENOTYPE PHENOTYPES physiology PROTEIN METABOLISM Quaternary Ammonium Compounds Quaternary Ammonium Compounds - pharmacology regulator genes REGULATORY GENES RESTRICTION MAPPING SECUENCIA NUCLEOTIDICA SEQUENCE NUCLEOTIDIQUE TRANSCRIPTION FACTORS Transcription Factors - genetics Transcription Factors - physiology
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Summary:	The gene nmrA of Aspergillus nidulans has been isolated and found to be a homolog of the Neurospora crassa gene nmr-1, involved in nitrogen metabolite repression. Deletion of nmrA results in partial derepression of activities subject to nitrogen repression similar to phenotypes observed for certain mutations in the positively acting areA gene
Bibliography:	F61 1997091996 F30 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 Corresponding author. Mailing address: Department of Genetics, University of Melbourne, Parkville, Victoria 3052, Australia. Phone: 61 3 9344 5140. Fax: 61 3 9344 5139. E-mail: hynes.lab@genetics.unimelb.edu.au.
ISSN:	0021-9193 1067-8832 1098-5530
DOI:	10.1128/jb.180.7.1973-1977.1998