Pars plana lensectomy and iris-claw Artisan intraocular lens implantation in patients with Marfan syndrome

• Published in: Oman journal of ophthalmology Vol. 16; no. 1; pp. 64 - 68
• Main Authors: Karjou, Zahra, Karimi, Saeed, Yaghoobi, Mohadeseh, Nikkhah, Homayoun, Safi, Sare
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.01.2023; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Care and treatment; Complications and side effects; crystalline lens subluxation; Intraocular lenses; iris-claw artisan intraocular lens; Marfan syndrome; Original; pars plana lensectomy; Visual acuity; pars plana lensectomy; Crystalline lens subluxation; iris-claw Artisan intraocular lens; Marfan syndrome
• ISSN: 0974-620X; 0974-7842
• DOI: 10.4103/ojo.ojo_25_22

RATIONAL: The rationale of this study was to evaluate the visual and anatomical outcomes of pars plana lensectomy and iris-claw Artisan intraocular lens (IOL) implantation in patients with subluxated crystalline lenses secondary to Marfan syndrome. MATERIALS AND METHODS: In this retrospective case series, we evaluate the records of 21 eyes of 15 patients with Marfan syndrome and moderate-to-severe crystalline lens subluxation who underwent pars plana lensectomy/anterior vitrectomy and implantation of iris-claw Artisan IOL at referral hospital from September 2015 to October 2019. RESULTS: Twenty-one eyes of 15 patients (10 males and five females) with a mean age of 24.47 ± 19.14 years were included. Mean best-corrected visual acuity was improved from 1.17 ± 0.55 logMAR to 0.64 ± 0.71 logMAR at the final follow-up visit (P < 0.001). The mean intraocular pressure did not change significantly (P = 0.971). The final refraction showed a mean sphere of 0.54 ± 2.46 D and a mean cylinder of 0.81 ± 1.03 at the mean axis of 57.92 ± 58.33 degrees. One eye developed rhegmatogenous retinal detachment 2 months after surgery. CONCLUSIONS: Pars plana lensectomy and iris-claw Artisan IOL implantation seem to be a useful, impressive, and safe procedure with a low rate of complications in Marfan patients with moderate-to-severe crystalline lens subluxation. Visual acuity was significantly improved with acceptable anatomical and refractive outcomes.