Non-small cell lung cancer (NSCLC): A review of risk factors, diagnosis, and treatment

Lung cancer remains the leading cause of cancer deaths. Non-small cell lung cancer (NSCLC) is the most frequent subtype of lung cancer. Surgery, radiation, chemotherapy, immunotherapy, or molecularly targeted therapy is used to treat NSCLC. Nevertheless, many patients who accept surgery likely devel...

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Published inMedicine (Baltimore) Vol. 102; no. 8; p. e32899
Main Authors Alduais, Yaser, Zhang, Haijun, Fan, Fan, Chen, Jing, Chen, Baoan
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins 22.02.2023
Subjects
Carcinoma, Non-Small-Cell Lung - drug therapy
Combined Modality Therapy
Humans
Immunotherapy
Lung Neoplasms - pathology
Narrative Review
Risk Factors
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Summary:Lung cancer remains the leading cause of cancer deaths. Non-small cell lung cancer (NSCLC) is the most frequent subtype of lung cancer. Surgery, radiation, chemotherapy, immunotherapy, or molecularly targeted therapy is used to treat NSCLC. Nevertheless, many patients who accept surgery likely develop distant metastases or local recurrence. In recent years, targeted treatments and immunotherapy have achieved improvement at a breakneck pace. Therapy must be customized for each patient based on the specific medical condition, as well as other variables. It is critical to have an accurate NSCLC sub-classification for tailored treatment, according to the latest World Health Organization standards.
Bibliography:ObjectType-Article-2
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ISSN:0025-7974
1536-5964
1536-5964
DOI:10.1097/MD.0000000000032899