The predicted impact of private sector MMR vaccination on the burden of Congenital Rubella Syndrome

In many developing countries, Measles–Mumps–Rubella (MMR) vaccine is available through the private but not the public sectors, and there is no systematic rubella vaccination among adult women. In this paper, we extend previous modeling studies to demonstrate that in developing countries with a mediu...

Full description

Saved in:
Bibliographic Details
Published inVaccine Vol. 21; no. 21; pp. 2708 - 2719
Main Authors Vynnycky, E., Gay, N.J., Cutts, F.T.
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 20.06.2003
Elsevier
Elsevier Limited
Subjects
Adult
Autism
Biological and medical sciences
Children & youth
Congenital Rubella Syndrome
Developing Countries
Female
Human viral diseases
Humans
Immunization Programs
Infectious diseases
Male
Mathematical model
Measles
Measles-Mumps-Rubella Vaccine - therapeutic use
Medical sciences
MMR vaccination
Mumps
Private Sector
Rubella Syndrome, Congenital - epidemiology
Rubella Syndrome, Congenital - prevention & control
Time Factors
Transmission dynamics
Tropical medicine
Vaccination
Vaccines
Viral diseases
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
Congenital Rubella Syndrome
MMR vaccination
Mathematical model
Transmission dynamics
Human
Infection
Immunoprophylaxis
Rubella
Congenital
Viral disease
Vaccination
Adult
Female
Mixed vaccine
Predictive factor
Private sector
Online AccessGet full text

Cover

More Information
Summary:In many developing countries, Measles–Mumps–Rubella (MMR) vaccine is available through the private but not the public sectors, and there is no systematic rubella vaccination among adult women. In this paper, we extend previous modeling studies to demonstrate that in developing countries with a medium–high force of infection (200–400/1000 per year), current levels of private sector MMR coverage (<60%) would lead to increases in the incidence of Congenital Rubella Syndrome (CRS) both among unvaccinated individuals and the general population even when mixing between vaccinated and unvaccinated individuals is fairly minimal. Our findings highlight the need for countries to establish surveillance of trends in susceptibility to rubella and CRS incidence and perhaps introduce rubella vaccination among women of child-bearing age.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:0264-410X
1873-2518
DOI:10.1016/S0264-410X(03)00229-9