Etanercept in erythema nodosum leprosum
One of the biggest challenges in treating leprosy is the control of reaction events. Patients with lepromatous leprosy may present reaction type II, or erythema nodosum leprosum, during treatment, and this reaction can remain in a recurrent form after being released from the hospital, requiring the...
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Published in | Anais brasileiros de dermatología Vol. 92; no. 4; pp. 575 - 577 |
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Main Authors | , , , |
Format | Journal Article |
Language | English Portuguese |
Published |
Brazil
Sociedade Brasileira de Dermatologia
01.07.2017
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Subjects | |
Online Access | Get full text |
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Summary: | One of the biggest challenges in treating leprosy is the control of reaction events. Patients with lepromatous leprosy may present reaction type II, or erythema nodosum leprosum, during treatment, and this reaction can remain in a recurrent form after being released from the hospital, requiring the use of thalidomide and/or prednisone for long periods of time, in turn increasing the risk of side effects. Two reports of the use of antiTNF to treat erythema nodosum leprosum were found in the literature. A good response was found after an assay with infliximab and etanercept. This study reports on a patient with lepromatous leprosy and recurrent reaction, controlled by using etanercept and a 10-month follow-up, with the interruption of thalidomide and the maintenance of prednisone at 10 mg/day. |
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Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 |
ISSN: | 0365-0596 1806-4841 1806-4841 0365-0596 |
DOI: | 10.1590/abd1806-4841.20175471 |