Idiopathic, asymptomatic, and durable blood hypereosinophilia—still many unknowns

In line with the Chen study,1 we have found no difference in serum levels of IL-4, IL-5, IL-13, IL-17, thymus activation and regulated chemokine, and eotaxin between on and off therapy subjects with HEUS, FIP1L1-PDGFRA-negative HES, and FIP1L1-PDGFRA-positive HES (data not published). Personally, we...

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Published inJournal of allergy and clinical immunology Vol. 133; no. 3; pp. 932 - 933
Main Authors Helbig, Grzegorz, MD, PhD, Kyrcz-Krzemień, Sławomira, MD, PhD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.2014
Elsevier Limited
Subjects
Allergy and Immunology
Eosinophilia - diagnosis
Female
Flow cytometry
Humans
Male
Medical treatment
Patients
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Summary:In line with the Chen study,1 we have found no difference in serum levels of IL-4, IL-5, IL-13, IL-17, thymus activation and regulated chemokine, and eotaxin between on and off therapy subjects with HEUS, FIP1L1-PDGFRA-negative HES, and FIP1L1-PDGFRA-positive HES (data not published). Personally, we offer corticosteroids in selected patients with a high number of circulating blood eosinophils to prevent organ damage.
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ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2013.12.023