Trihexyphenidyl Misuse in Delusional Disorder

ABSTRACT Trihexyphenidyl is an anticholinergic medication that is routinely used for the management of extrapyramidal symptoms in patients who receive antipsychotic medications. Trihexyphenidyl has been reported to be abused by some patients, who start to take it in increasing doses and tend to repo...

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Bibliographic Details
Published inJournal of neurosciences in rural practice Vol. 9; no. 3; pp. 428 - 430
Main Authors Mahal, Pankaj, Nishanth, K. N., Mahapatra, Ananya, Sarkar, Siddharth, Balhara, Yatan Pal Singh
Format Journal Article
LanguageEnglish
Published A-12, Second Floor, Sector -2, NOIDA -201301, India Thieme Medical and Scientific Publishers Private Ltd 01.07.2018
Wolters Kluwer India Pvt. Ltd
Thieme Medical Publishers Inc
Medknow Publications & Media Pvt Ltd
Subjects
Anesthesia
Cardiac arrhythmia
Case Report
Consent
Delusional disorder
Dopamine
Drug abuse
Drug dosages
Headaches
Mental disorders
Patients
Prescription drugs
Psychiatry
Psychosis
Psychotropic drugs
Sleep
dependence
Delusional disorder
trihexyphenidyl
misuse
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Summary:ABSTRACT Trihexyphenidyl is an anticholinergic medication that is routinely used for the management of extrapyramidal symptoms in patients who receive antipsychotic medications. Trihexyphenidyl has been reported to be abused by some patients, who start to take it in increasing doses and tend to report a sensation of relaxation or pleasure with this medication. Hence, whether trihexyphenidyl should be considered a psychoactive substance and whether nonprescription misuse of this medication should be considered under the purview of substance use disorders need further clarity. We present here two cases of trihexyphenidyl misuse which developed in the context of persistent delusional disorders and highlight the challenges in diagnosis in such a situation.
ISSN:0976-3147
0976-3155
DOI:10.4103/jnrp.jnrp_569_17