Associations of health-related quality of life with depression and stigma in MERS-CoV survivors during the recovery period

• Published in: Medicine (Baltimore) Vol. 101; no. 25; p. e29440
• Main Authors: Ahn, So-Hyun, Kim, Jeong Lan, Lee, So Hee, Park, Hye Yoon, Lee, Jung Jae, Lee, Haewoo
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 24.06.2022; Wolters Kluwer
• Subjects: Cohort Studies; Depression - epidemiology; Fatigue Syndrome, Chronic; Humans; Middle East Respiratory Syndrome Coronavirus; Observational Study; Quality of Life; Survivors
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000029440

We explored factors related to health-related quality of life (HRQOL), including psychiatric symptoms and stigma related to Middle East respiratory syndrome coronavirus (MERS-CoV) infection, among MERS-CoV survivors during the recovery period.Sixty-three MERS-COV survivors were recruited from five hospitals for a cohort study, one year after their infection in 2015. The subjects' demographic information and medical conditions associated with MERS-CoV were recorded. HRQOL was evaluated using the Short Form-8 Health Survey (SF-8). Depression, post-traumatic stress symptoms, chronic fatigue, and perceived stigma were assessed using several questionnairesThe mean physical component summary (PCS) and mean mental component summary (MCS) of the SF-8 score were below 50 T (43.47 ± 9.60, 45.74 ± 10.18). Depression, chronic fatigue, posttraumatic stress symptoms and stigma were negatively correlated with the SF-8 PCS and MCS. Multivariate logistic regression analysis showed that the PCS was associated with stigma (OR 8.66, 95% CI 1.96-38.23), whereas MCS was associated with depression (OR 26.62, 95% CI 3.56-198.85).The estimated HRQOL of MERS-CoV survivors during recovery was poor and appeared to be associated with depression and MERS-related stigma.