The effect of cardiac rehabilitation prescription on medication complications and ET-1, WMSI in elderly patients with coronary heart disease

• Published in: Journal of cardiothoracic surgery Vol. 19; no. 1; pp. 630 - 11
• Main Authors: Li, Min, Zhuo, Xiaojun, Shao, Lihui, Yin, Lin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.11.2024; BioMed Central; BMC
• Subjects: Aerobics; Aged; Aged patients; Angina pectoris; Blood pressure; Cardiac function; Cardiac patients; Cardiac Rehabilitation - methods; Cardiology; Cardiovascular disease; Compliance; Coronary artery disease; Coronary Disease - drug therapy; Coronary Disease - rehabilitation; Coronary heart disease; Coronary vessels; Diseases; Endothelin; Endothelin 1; Endothelin-1 - blood; Exercise intensity; Exercise therapy; Exercise Therapy - methods; Female; Geriatrics; Health services; Heart attacks; Heart diseases; Heart rate; Heart rehabilitation prescription; Humans; Intervention; Kinases; Male; Medication complications; Metabolic syndrome; Muscle pain; Old age; Older people; Patient compliance; Patients; Physical fitness; Physical therapy; Prescription drugs; Quality of life; Rehabilitation; Wall motion score; Wall motion score; Heart rehabilitation prescription; Medication complications; Coronary heart disease; Old age; Endothelin-1
• ISSN: 1749-8090; 1749-8090
• DOI: 10.1186/s13019-024-03124-9

To explore the effects of cardiac rehabilitation prescriptions on medication complications, Endothelin 1 (ET-1), and Wall Motion Score Index (WMSI) in elderly patients with coronary heart disease. 98 elderly patients with coronary heart disease admitted to the Department of Cardiology of a hospital from January 2020 to June 2022 are selected. According to the red and blue ball method, 98 research subjects are divided into a control group and an observation group. The control group receives routine treatment and exercise intervention, while the observation group receives cardiac rehabilitation prescriptions. After a follow-up of 6 months, the incidence of medication complications between the two groups is compared. The changes in ET-1 and WMSI levels are compared before treatment, 1 month, 3 months, and 6 months after treatment. The two groups had no significant difference in ET-1 and WMSI levels before intervention. After intervention, both groups showed significant reductions in ET-1 and WMSI compared with baseline. The ET-1 of the observation group decreased significantly faster than the control group after 1 month, 3 months, and 6 months of intervention. The WMSI decreased more significantly at 6 months. The repeated measurement variance showed that there was a significant difference in the trend of ET-1 changes between the two groups, while the difference between the WMSI groups was not significant. The incidence of medication complications in the observation group was 10.20%, significantly lower than the 26.53% in the control group. Cardiac rehabilitation prescriptions can reduce the incidence of medication complications in elderly patients with coronary heart disease. It can reduce ET-1 levels faster, improve myocardial motor function, which has better myocardial function and medication safety than conventional treatment.