Smokeless tobacco consumption among women of reproductive age: a systematic review and meta-analysis

• Published in: BMC public health Vol. 24; no. 1; p. 1361
• Main Authors: Itumalla, Ramaiah, Khatib, Mahalaqua Nazli, Gaidhane, Shilpa, Zahiruddin, Quazi Syed, Gaidhane, Abhay M, Neyazi, Ahmad, Hassam, Ahmad Farshid, Satapathy, Prakasini, Rustagi, Sarvesh, Kukreti, Neelima, Padhi, Bijaya Kumar
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.05.2024; BioMed Central; BMC
• Subjects: Adult; Age; Age groups; Analysis; Birth weight; Chewing tobacco; Childrens health; Cross-sectional studies; Developing countries; Fatalities; Female; Fetuses; Health aspects; Health risk assessment; Health risks; Heterogeneity; Humans; Infertility; LDCs; Low birth weight; Maternal & child health; Meta-analysis; Observational studies; Pregnancy; Pregnancy complications; Premature birth; Prevalence; Public health; Sensitivity analysis; Smokeless tobacco; Smoking and women; Software; Statistical analysis; Statistics; Subgroups; Sustainable development goals; Systematic Review; Tobacco; Tobacco Use - epidemiology; Tobacco, Smokeless - statistics & numerical data; Women of reproductive age; Womens health; India; Sustainable development goals; Chewing tobacco; Public health; Smokeless tobacco; Women of reproductive age; Meta-analysis
• ISSN: 1471-2458; 1471-2458
• DOI: 10.1186/s12889-024-18840-z

Smokeless tobacco (SLT) poses many negative health impacts. Despite its longstanding presence in societies across the world, the health implications of SLT have only been rigorously studied in recent decades. This systematic review and meta-analysis aimed to consolidate existing research to provide a comprehensive understanding of the global prevalence of SLT use among women of reproductive age. Relevant articles were extracted from databases such as PubMed, EMBASE, Web of Science, and Scopus from their inception until November 11, 2023. Observational studies reporting the number of SLT users among women of reproductive age were included. The quality of the studies was assessed using the Joanna Briggs Institute (JBI) tool. The meta-analysis used a random-effects model to determine SLT prevalence, supported by statistical tools like forest plots, I statistics, and sensitivity analyses to ensure the accuracy and comprehensiveness of the results. All statistical analyses were performed in R version 4.3. From 10 studies involving 2,053,667 participants, a pooled prevalence for SLT use among women of reproductive age was found to be 9.3% (95% CI: 0.038 to 0.21), with significant heterogeneity among studies (I  = 100%). Publication bias was suspected among the studies. Sensitivity analysis and subgroup analysis couldn't resolve the heterogeneity. Our analysis shows a significant prevalence of SLT use in women of reproductive age, especially in low socioeconomic and developing countries like India, Pakistan, and Nepal. For women of reproductive age, the use of smokeless tobacco (SLT) can lead to infertility, pregnancy complications, and adverse fetal outcomes, including low birth weight and preterm birth. The results highlight the necessity for specific public health measures and policy changes to decrease SLT consumption among reproductive-age women. Further studies are needed to investigate the reasons behind SLT usage in this group and to assess the impact of intervention strategies, to guide more effective public health initiatives and policies.