Application of Advanced Nanomaterials for Kidney Failure Treatment and Regeneration

The implementation of nanomedicine not only provides enhanced drug solubility and reduced off-target adverse effects, but also offers novel theranostic approaches in clinical practice. The increasing number of studies on the application of nanomaterials in kidney therapies has provided hope in a mor...

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Published inMaterials Vol. 14; no. 11; p. 2939
Main Authors Eftekhari, Aziz, Maleki Dizaj, Solmaz, Ahmadian, Elham, Przekora, Agata, Hosseiniyan Khatibi, Seyed Mahdi, Ardalan, Mohammadreza, Zununi Vahed, Sepideh, Valiyeva, Mahbuba, Mehraliyeva, Sevil, Khalilov, Rovshan, Hasanzadeh, Mohammad
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 29.05.2021
MDPI
Subjects
Aluminum
Bedrock
Bioengineering
Biomedical materials
Carbon nanotubes
Cartilage
Clinical medicine
Collagen
exosomes
Health services
kidney regeneration
Kidneys
Mechanical properties
Membranes
Nanocomposites
nanofibers
Nanomaterials
Nanoparticles
Nanotechnology
nanovesicles
Polylactic acid
Polymers
Polyvinyl alcohol
Regeneration
Review
Skin
Stem cells
therapeutic nanomedicine
Tissue engineering
Transplants & implants
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Summary:The implementation of nanomedicine not only provides enhanced drug solubility and reduced off-target adverse effects, but also offers novel theranostic approaches in clinical practice. The increasing number of studies on the application of nanomaterials in kidney therapies has provided hope in a more efficient strategy for the treatment of renal diseases. The combination of biotechnology, material science and nanotechnology has rapidly gained momentum in the realm of therapeutic medicine. The establishment of the bedrock of this emerging field has been initiated and an exponential progress is observed which might significantly improve the quality of human life. In this context, several approaches based on nanomaterials have been applied in the treatment and regeneration of renal tissue. The presented review article in detail describes novel strategies for renal failure treatment with the use of various nanomaterials (including carbon nanotubes, nanofibrous membranes), mesenchymal stem cells-derived nanovesicles, and nanomaterial-based adsorbents and membranes that are used in wearable blood purification systems and synthetic kidneys.
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ISSN:1996-1944
1996-1944
DOI:10.3390/ma14112939