Stimulation of the Human RAD51 Nucleofilament Restricts HIV-1 Integration In Vitro and in Infected Cells

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Published inJournal of Virology Vol. 86; no. 1; pp. 513 - 526
Main Authors COSNEFROY, O, TOCCO, A, BONOT, P, SAN FILIPPO, J, LITVAK, S, LE CAM, E, RETHWILM, A, FLEURY, H, CONNELL, P. P, SUNG, P, DELELIS, O, ANDREOLA, M. L, LESBATS, P, PARISSI, V, THIERRY, S, CALMELS, C, WIKTOROWICZ, T, REIGADAS, S, KWON, Y, DE CIAN, A, DESFARGES, S
Format Journal Article
LanguageEnglish
Published Washington, DC American Society for Microbiology 01.01.2012
Subjects
Biological and medical sciences
Cell Line
Cellular Response to Infection
DNA Repair
DNA, Single-Stranded
DNA, Single-Stranded - chemistry
DNA, Single-Stranded - genetics
DNA, Single-Stranded - metabolism
Down-Regulation
Fundamental and applied biological sciences. Psychology
HIV Infections
HIV Infections - enzymology
HIV Infections - genetics
HIV Infections - virology
HIV Integrase
HIV Integrase - genetics
HIV Integrase - metabolism
HIV-1
HIV-1 - enzymology
HIV-1 - genetics
HIV-1 - physiology
Humans
Life Sciences
Microbiology
Microbiology and Parasitology
Miscellaneous
Protein Binding
Rad51 Recombinase
Rad51 Recombinase - chemistry
Rad51 Recombinase - genetics
Rad51 Recombinase - metabolism
Recombination, Genetic
Virology
Virus Integration
Virus
Human
HIV-1 virus
Retroviridae
Human immunodeficiency virus
Infected cell
Lentivirus
In vitro
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PMCID: PMC3255893
Present address: Institute of Microbiology (IMUL), Bugnon 48—CHUV, Lausanne, Switzerland.
O.C. and A.T. contributed equally to this article.
ISSN:0022-538X
1098-5514
DOI:10.1128/JVI.05425-11