Dechlorane Plus and related compounds in aquatic and terrestrial biota: a review

• Published in: Analytical and bioanalytical chemistry Vol. 404; no. 9; pp. 2625 - 2637
• Main Authors: Feo, M. L., Barón, E., Eljarrat, E., Barceló, D.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.11.2012; Springer
• Subjects: Analysis; Analytical Chemistry; Animals; Bioaccumulation; Biochemistry; Biota; Characterization and Evaluation of Materials; Chemical properties; Chemistry; Chemistry and Materials Science; Chromatography, Gas - methods; Contaminants; Environmental Monitoring - methods; Environmental Pollutants - analysis; Environmental Pollutants - toxicity; Fireproofing agents; Fishes; Flame retardants; Flame Retardants - analysis; Flame Retardants - toxicity; Food Science; Human; Humans; Hydrocarbons, Chlorinated - analysis; Hydrocarbons, Chlorinated - toxicity; Isomers; Laboratory Medicine; Lipophilicity; Mass spectrometry; Mass Spectrometry - methods; Mathematical analysis; Mirex; Monitoring/Environmental Analysis; Physiological aspects; Polycyclic Compounds - analysis; Polycyclic Compounds - toxicity; Review; Summaries; Gas chromatography; Halogenated flame retardants; Tandem mass spectrometry; High-resolution mass spectrometry; Halogenated norbornenes; Biota
• ISSN: 1618-2642; 1618-2650
• DOI: 10.1007/s00216-012-6161-x

Dechlorane Plus, dechlorane 602, dechlorane 603 and dechlorane 604 are flame retardants that have been used for a long time as a substitute for mirex, but they have not been noticed as environmental contaminants until recently (2006). Regardless of their large molecular size and very high lipophilicity (log K OW  > 9), Dechlorane Plus and related compounds have been detected in different aquatic and terrestrial species, supporting their bioaccumulation and biomagnification. Moreover, some studies showed different behaviour of the syn -Dechlorane Plus and anti -Dechlorane Plus isomers in the environment and different biomagnification factors in biota. This review describes the different analytical approaches applied to the determination of Dechlorane Plus and related compounds. Moreover, a summary of their levels in aquatic and terrestrial biota, as well as in humans, is presented, showing also current research results on their bioaccumulation and biomagnification potential. Finally, isomer-specific bioaccumulation of Dechlorane Plus is also discussed.