Multicomponent Synthesis of Unsymmetrical Unsaturated N-Heterocyclic Carbene Precursors and Their Related Transition-Metal Complexes
A low‐cost, modular, and easily scalable multicomponent procedure affording access in good yields and excellent selectivity (up to 93 %) to a wide range of (a)chiral unsymmetrical 1‐aryl‐3‐cycloalkyl‐imidazolium salts is disclosed. Electronic and steric properties of the corresponding unsymmetrical...
Saved in:
Published in | Angewandte Chemie (International ed.) Vol. 52; no. 52; pp. 14103 - 14107 |
---|---|
Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
23.12.2013
WILEY‐VCH Verlag Wiley Wiley Subscription Services, Inc Wiley-VCH Verlag |
Edition | International ed. in English |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | A low‐cost, modular, and easily scalable multicomponent procedure affording access in good yields and excellent selectivity (up to 93 %) to a wide range of (a)chiral unsymmetrical 1‐aryl‐3‐cycloalkyl‐imidazolium salts is disclosed. Electronic and steric properties of the corresponding unsymmetrical unsaturated N‐heterocyclic carbene (U2‐NHC) ligands were evaluated and evidenced strong electron donor ability, high steric discrimination, and modular steric demand.
A low‐cost, modular, and easily scalable multicomponent procedure, affording access to a wide range of (a)chiral unsymmetrical 1‐aryl‐3‐cycloalkyl‐imidazolium salts in good yields and excellent selectivities, is disclosed. Electronic and steric properties of the corresponding unsymmetrical unsaturated N‐heterocyclic carbene (U2‐NHC) ligands were evaluated and evidenced strong electron‐donor ability, high steric discrimination, and modular steric demand. |
---|---|
Bibliography: | M.M. and O.B. thank Rennes metropole (Grants to P.Q. and J.-C.L.), the Région-Bretagne (Grants to C.J.), the Agence Nationale de la Recherche (Grant ANR-12-CD2I-0002 CFLOW-OM), and Dr. D. Martin for helpful discussions. istex:EB1941D51429C82CF60AD9134E8E2CC9D10CBC93 Agence Nationale de la Recherche - No. ANR-12-CD2I-0002 Région-Bretagne ArticleID:ANIE201308873 Rennes metropole ark:/67375/WNG-L2W097SM-S M.M. and O.B. thank Rennes metropole (Grants to P.Q. and J.‐C.L.), the Région‐Bretagne (Grants to C.J.), the Agence Nationale de la Recherche (Grant ANR‐12‐CD2I‐0002 CFLOW‐OM), and Dr. D. Martin for helpful discussions. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1433-7851 1521-3773 |
DOI: | 10.1002/anie.201308873 |