Effects of Chloroformic Extracts from Washed and Unwashed Papaya Seeds (Carica papaya) on the Sperm Concentration of Dogs
Papaya seeds (Carica papaya Linn) have been found to have a significant effect on sperm characteristics in some mammals, including humans, but no studies have investigated the effects on dogs. In the present study, a significant decrease in sperm concentration was observed in a group of dogs treated...
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Published in | Reproduction in domestic animals Vol. 45; no. 6; pp. 1126 - 1129 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.12.2010
Blackwell |
Subjects | |
Online Access | Get full text |
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Summary: | Papaya seeds (Carica papaya Linn) have been found to have a significant effect on sperm characteristics in some mammals, including humans, but no studies have investigated the effects on dogs. In the present study, a significant decrease in sperm concentration was observed in a group of dogs treated with extracts from washed papaya seeds, but no decrease was observed in the group of dogs treated with non‐washed seeds. An important effect of extract components from washed seeds such as fatty acids is probably involved in the reduction of sperm production because of Sertoli cell damage, as has been suggested for langur monkeys. Dilution of the active components in the non‐washed papaya seeds or interference with some of the components may reduce the expected effect on spermatogenesis. This first report on the effects of a chloroformic extract of papaya seeds in dogs suggests that an increased dose is necessary to achieve azoospermia. |
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Bibliography: | http://dx.doi.org/10.1111/j.1439-0531.2009.01503.x ArticleID:RDA1503 istex:DB32E5C630F95A1C9E2FC841ABD5E25E7B940926 ark:/67375/WNG-2D3F5P7M-1 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-News-1 ObjectType-Feature-3 content type line 23 |
ISSN: | 0936-6768 1439-0531 |
DOI: | 10.1111/j.1439-0531.2009.01503.x |