The impact of exercise duration and intensity on the release of cardiac biomarkers
Numerous studies have observed cardiac biomarker release with prolonged exercise. Despite this, we are unsure as to the constituent aspects of any given exercise bout that may be important in promoting cardiac biomarker release. This study examined the influence of exercise duration and intensity on...
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Published in | Scandinavian journal of medicine & science in sports Vol. 21; no. 2; pp. 244 - 249 |
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Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.04.2011
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Subjects | |
Online Access | Get full text |
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Summary: | Numerous studies have observed cardiac biomarker release with prolonged exercise. Despite this, we are unsure as to the constituent aspects of any given exercise bout that may be important in promoting cardiac biomarker release. This study examined the influence of exercise duration and intensity on the appearance of cardiac biomarkers. Twenty‐one subjects ran for 45, 90 and 180 min at 85% and 95% of their individual anaerobic threshold on six different days randomized. Cardiac troponin I (cTnI) and N‐terminal pro‐brain natiuretic peptide (NT‐proBNP) were assayed from blood samples collected before, 30 min and 3 h post‐exercise. NT‐proBNP was elevated after all exercise trials (range before: 21–32; range post: 38–67 ng/L). Peak post‐exercise concentrations of NT‐proBNP were associated with exercise duration (P=0.049), but not exercise intensity (P=0.451). cTnI was elevated after all exercise trials (range before: 0.007–0.011; range post: 0.008–0.021 μg/L). Peak post‐exercise concentrations of cTnI were associated with exercise duration (P=0.003) and intensity (P=0.037). Data suggest that while both cTnI and NT‐proBNP increased after all exercise trials, the mediating effect of duration influenced both NT‐proBNP and cTnI while intensity influenced only cTnI. |
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Bibliography: | istex:D32DC8D159CE05D193E69AAE1FD0C92B15E28A4C ark:/67375/WNG-7SKJXH88-N ArticleID:SMS1042 a [Correction made here after initial online publication] This article was published online on 17th November 2009. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected 17th December 2009. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 |
ISSN: | 0905-7188 1600-0838 |
DOI: | 10.1111/j.1600-0838.2009.01042.x |