Ultra-Sensitive and Specific Detection of S. aureus Bacterial Cultures Using an Oligonucleotide Probe Integrated in a Lateral Flow-Based Device

The identification of pathogens causing infectious diseases is still based on laborious and time-consuming techniques. Therefore, there is an urgent need for the development of novel methods and devices that can considerably reduce detection times, allowing the health professionals to administer the...

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Published inDiagnostics (Basel) Vol. 11; no. 11; p. 2022
Main Authors Machado, Isabel, Goikoetxea, Garazi, Alday, Enara, Jiménez, Tania, Arias-Moreno, Xabier, Hernandez, Frank J., Hernandez, Luiza I.
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 31.10.2021
MDPI
Subjects
Acids
Bacteria
Bacterial infections
detection
Enzymes
Laboratories
lateral flow strips
Nosocomial infections
nuclease activity
nucleic acid probe
Pathogens
S. aureus
Staphylococcus infections
Streptococcus infections
Madrid Spain
Spain
detection
lateral flow strips
nuclease activity
S. aureus
nucleic acid probe
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Summary:The identification of pathogens causing infectious diseases is still based on laborious and time-consuming techniques. Therefore, there is an urgent need for the development of novel methods and devices that can considerably reduce detection times, allowing the health professionals to administer the right treatment at the right time. Lateral flow-based systems provide fast, cheap and easy to use alternatives for diagnosis. Herein, we report on a lateral flow approach for specifically detecting S. aureus bacteria within 6 h.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics11112022