Detoxification of Deoxynivalenol via Glycosylation Represents Novel Insights on Antagonistic Activities of Trichoderma when Confronted with Fusarium graminearum

• Published in: Toxins Vol. 8; no. 11; p. 335
• Main Authors: Tian, Ye, Tan, Yanglan, Liu, Na, Yan, Zheng, Liao, Yucai, Chen, Jie, de Saeger, Sarah, Yang, Hua, Zhang, Qiaoyan, Wu, Aibo
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15.11.2016; MDPI
• Subjects: biological control; Biological Control Agents; Coculture Techniques; Fusarium - growth & development; Fusarium - metabolism; Fusarium graminearum; Glycosylation; modified mycotoxin; Mycelium - growth & development; mycotoxin; Solanum tuberosum; toxigenic Fusarium; Trichoderma; Trichoderma - growth & development; Trichothecenes - metabolism; Trichoderma; mycotoxin; biological control; modified mycotoxin; toxigenic Fusarium
• ISSN: 2072-6651; 2072-6651
• DOI: 10.3390/toxins8110335

Deoxynivalenol (DON) is a mycotoxin mainly produced by the complex, which are important phytopathogens that can infect crops and lead to a serious disease called head blight (FHB). As the most common B type trichothecene mycotoxin, DON has toxic effects on animals and humans, which poses a risk to food security. Thus, efforts have been devoted to control DON contamination in different ways. Management of DON production by strains as a biological control-based strategy has drawn great attention recently. In our study, eight selected strains were evaluated for their antagonistic activities on by dual culture on potato dextrose agar (PDA) medium. As potential antagonists, strains showed prominent inhibitory effects on mycelial growth and mycotoxin production of . In addition, the modified mycotoxin deoxynivalenol-3-glucoside (D3G), which was once regarded as a detoxification product of DON in plant defense, was detected when were confronted with . The occurrence of D3G in and interaction was reported for the first time, and these findings provide evidence that strains possess a self-protection mechanism as plants to detoxify DON into D3G when competing with .