Reduction of facial pigmentation of melasma by topical lignin peroxidase: A novel fast-acting skin-lightening agent

• Published in: Experimental and therapeutic medicine Vol. 9; no. 2; pp. 341 - 344
• Main Authors: ZHONG, SHAO-MIN, SUN, NAN, LIU, HUI-XIAN, NIU, YUE-QING, WU, YAN
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01.02.2015; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Dermatologic agents; Dermatology; Drug therapy; emulsions; Enzymes; Formulae, receipts, prescriptions; Fungi; Genetic aspects; Health aspects; Hormone replacement therapy; Lignin; lignin peroxidase; melanin; Melanosis; melasma; Patients; Peroxidase; Physiological aspects; Risk factors; skin lightening; Statistical analysis; statistics; Sunscreen; Variance analysis; China; Beijing China; United States > US; melasma; lignin peroxidase; emulsions; melanin; skin lightening; statistics

The aim of the present study was to evaluate the efficacy and safety of lignin peroxidase (LIP) as a skin-lightening agent in patients with melasma. A self-controlled clinical study was performed in 31 women who had melasma on both sides of the face. This study involved 8 weeks of a full-face produc...