Effect of Dyslipidaemia and Metabolic Function in Coronary Heart Disease with Type 2 Diabetes Mellitus - In Tertiary Care Center

• Published in: Journal of pharmacy & bioallied science Vol. 17; no. Suppl 1; pp. S913 - S915
• Main Authors: Singh, Akansha, Ambad, Ranjit S., Jha, Roshan Kumar
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer - Medknow 01.05.2025; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Edition: 2
• Subjects: Analysis; Cardiovascular disease; Cardiovascular diseases; Coronary artery disease; Coronary heart disease; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes therapy; Dyslipidemia; Health aspects; Heart diseases; high-density lipoprotein; Low density lipoproteins; low-density lipoprotein; Metabolic disorders; Metabolism; Morbidity; Mortality; Study Protocol; Survival; Type 2 diabetes; type 2 diabetes mellitus; very low density lipoprotein; type 2 diabetes mellitus; cardiovascular disease; very low density lipoprotein; Coronary heart disease; high-density lipoprotein; low-density lipoprotein
• ISSN: 0976-4879; 0975-7406
• DOI: 10.4103/jpbs.jpbs_1975_24

ABSTRACT Introduction: T2DM is strongly associated with an increased prevalence of cardiovascular disease (CVD). It has been established that CVD is the main cause of mortality among patients with type 2 diabetes mellitus (T2DM) contributing to 80% of fatal outcomes. The consistent relationship between T2DM and CVD is well-established in observational studies, meta-analyses, and has an easily discernible biological mechanism. Aim and Objectives: This was a cross-sectional study consisting of 100 subjects of diabetic and non-diabetic with CHD attending medicine outpatient department (OPD). Result and Conclusion: The study highlights that diabetes significantly exacerbates the metabolic and cardiovascular risks in coronary heart disease (CHD) patients, affecting lipid profiles, glycemic control, and long-term survival. Effective management of these parameters is crucial to improving outcomes in diabetic CHD patients. Postoperative morbidity and early mortality were not substantially affected by diabetes; however, long-term survival in diabetic CHD patients was markedly diminished, highlighting the enduring effects of diabetes on cardiovascular health.