Multilocular cystic renal oncocytoma-Awareness of an unusual morphologic variation

Background: Renal oncocytomas are benign epithelial tumors usually detected incidentally. They are typically solid,well-circumscribed,homogenous,mahoganybrown with a central stellate scar.Sometimes,they can have cystic degenerationand rarely present as a multilocular cyst which can be mistaken for o...

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Published inIndian journal of pathology & microbiology Vol. 64; no. 2; pp. 343 - 346
Main Authors Jagdale, Rakhi, Pol, Jaydeep
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer India Pvt. Ltd 01.04.2021
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Subjects
Adenoma, Oxyphilic - diagnosis
Adenoma, Oxyphilic - pathology
Aged
Carcinoma
Carcinoma, Renal Cell - diagnosis
Care and treatment
cystic
Cysts - pathology
Diagnosis
Diagnosis, Differential
Epithelial tumors
Humans
Immunohistochemistry
Kidney - pathology
Kidney cancer
Kidney Neoplasms - diagnosis
Kidney Neoplasms - pathology
Kidneys
Male
multilocular
oncocytoma
renal
Renal cell carcinoma
Tumors
India
renal
multilocular
Cystic
oncocytoma
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Summary:Background: Renal oncocytomas are benign epithelial tumors usually detected incidentally. They are typically solid,well-circumscribed,homogenous,mahoganybrown with a central stellate scar.Sometimes,they can have cystic degenerationand rarely present as a multilocular cyst which can be mistaken for other cystic renal carcinomas. Methods: We describe a case of incidentally detected multilocular cystic renal oncocytoma having an unusual gross appearance of multiloculation with perinephric fat invasion. The tumor exhibited tubulocystic architecture posed a diagnostic dilemma. Detailed study of multiple sections coupled with immunohisto chemistry helped elucidate the diagnosis. Till date, only eight cases of multicystic renal oncocytoma have been reported in the English literature. Conclusions: We emphasize the importance of awareness of this unusual morphologic variation to ensure correct diagnosis.
Bibliography:ObjectType-Case Study-2
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ISSN:0377-4929
0974-5130
DOI:10.4103/IJPM.IJPM_502_20