Emergence of taurine as a therapeutic agent for neurological disorders

• Published in: Neural regeneration research Vol. 19; no. 1
• Main Authors: Jangra, Ashok, Gola, Priyanka, Singh, Jiten, Gond, Pooja, Ghosh, Swarnabha, Rachamalla, Mahesh, Dey, Abhijit, Iqbal, Danish, Kamal, Mehnaz, Sachdeva, Punya, Jha, Saurabh, Ojha, Shreesh, Kumar, Dinesh, Jha, Niraj, Chopra, Hitesh, Tan, Shing
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.01.2024; Medknow Publications & Media Pvt. Ltd; Department of Pharmaceutical Sciences,Central University of Haryana,Mahendergarh,Haryana,India%Department of Biology,University of Saskatchewan,Saskatoon,SK,Canada%Department of Life Sciences,Presidency University,Kolkata,West Bengal,India%Department of Health Information Management,College of Applied Medical Sciences,Buraydah Private Colleges,Buraydah,Saudi Arabia%Department of Pharmaceutical Chemistry,College of Pharmacy,Prince Sattam Bin Abdulaziz University,Al-Kharj,Saudi Arabia%GloNeuro,Vishwakarma Road,Noida,India%Department of Biotechnology,School of Engineering & Technology(SET),Sharda University,Greater Noida,Uttar Pradesh,India%Department of Pharmacology and Therapeutics,College of Medicine and Health Sciences,United Arab Emirates University,Al Ain,United Arab Emirates%Department of Biotechnology,School of Engineering & Technology(SET),Sharda University,Greater Noida,Uttar Pradesh,India; Department of Biotechnology,School of Applied & Life Sciences(SALS),Uttaranchal University,Dehradun,India%Chitkara College of Pharmacy,Chitkara University,Punjab,India%UKM Medical Molecular Biology Institute,Universiti Kebangsaan Malaysia,Kuala Lumpur,Malaysia; School of Bioengineering & Biosciences,Lovely Professional University,Phagwara,India; Wolters Kluwer - Medknow
• Subjects: Neurological disorders; Review; epilepsy; spinal cord injury; antioxidant; neuroprotection; taurine; neurodegenerative disorders; oxidative stress; γ-amino butyric acid; y-amino butyric acid

Taurine is a sulfur-containing, semi-essential amino acid that occurs naturally in the body. It alternates between inflammation and oxidative stress-mediated injury in various disease models. As part of its limiting functions, taurine also modulates endoplasmic reticulum stress, Ca homeostasis, and...