Synthesis and its DNA Detecting Ability of Fluorescent Modified β-cyclodextrins having Long Chain Connected by pyrene Unit

Two kinds of pyrene modified β-cyclodextrins, which are different in linker parts to bind between β-cyclodextrin and pyrene unit, were synthesized. Those derivatives show different behavior for single and double strands of DNA, where short linker derivative shows no interaction for DNA, but longer l...

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Published inInternational Journal of the Society of Materials Engineering for Resources Vol. 16; no. 1_2; pp. 16 - 21
Main Authors MATSUMURA, Noriaki, KAGAYA, Masami, KONDO, Yoshihiko, AKAGAMI, Youichi, HAMADA, Fumio
Format Journal Article
LanguageEnglish
Published The Society of Materials Engineering for Resources of JAPAN 2009
Subjects
cyclodextrins
dsDNA
fluorescent spectra
linker
pyrene
ssDNA
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Summary:Two kinds of pyrene modified β-cyclodextrins, which are different in linker parts to bind between β-cyclodextrin and pyrene unit, were synthesized. Those derivatives show different behavior for single and double strands of DNA, where short linker derivative shows no interaction for DNA, but longer linker derivative indicates there are something interaction for DNA by intercalating of pyrene unit.
ISSN:1347-9725
1884-6629
DOI:10.5188/ijsmer.16.16