A comparison of yeast ribosomal protein gene DNA sequences

• Published in: Nucleic acids research Vol. 12; no. 22; pp. 8295 - 8312
• Main Authors: Teem, John L., Abovich, Nadja, Kaufer, Norbert F., Schwindinger, Willam F., Warner, Jonathan R., Levy, Allison, Woolford, John, Leer, R.J., Raamsdonk-Duin, M.M.C. Van, Mager, W.H, Planta, R.J., Schultz, L., Friesen, J.D., Fried, Howard, Rosbash, Michael
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 26.11.1984
• Subjects: Amino Acid Sequence; Applied sciences; Base Sequence; DNA, Fungal - genetics; Exact sciences and technology; Genes; Genes, Fungal; Other techniques and industries; Ribosomal Proteins - genetics; Saccharomyces - genetics; Saccharomyces cerevisiae; Saccharomyces cerevisiae - genetics; Species Specificity
• ISSN: 0305-1048; 1362-4962
• DOI: 10.1093/nar/12.22.8295

The DNA sequences of eight yeast ribosomal protein genes have been compared for the purpose of identifying homologous regions which may be involved in the coordinate regulation of ribosomal protein synthesis. A 12 bp homology was identified in the 5′ DNA sequence preceding the stuctural gene for 6 out of 8 yeast ribosomal protein genes. In each case the homologous sequence was found at a position approximately 300 bp preceding the transcription start of the ribosomal protein gene. This homology was not identified in any non-ribosomal protein gene examined. Additional homologies between ribosomal protein genes were identified in the transcribed regions, including the untranslated 5′ and 3′ DNA regions flanking the coding regions.