Gastrointestinal stromal tumor of the stomach in a child with a 3-year follow-up period—Case report

• Published in: International journal of surgery case reports Vol. 2; no. 6; pp. 114 - 117
• Main Authors: Miranda, Marcelo Eller, Alberti, Luiz Ronaldo, Tatsuo, Edson Samesima, Piçarro, Clécio, Rausch, Marcelo
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2011
• Subjects: Abdominal tumor; c-KIT; Children; Diagnosis; Gastric; Gastrointestinal bleeding; Gastrointestinal stromal tumor; Submucosal tumors; Surgery; Abdominal tumor; c-KIT; Gastrointestinal bleeding; Gastric; Submucosal tumors; Children; Diagnosis; Gastrointestinal stromal tumor
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2011.02.010

Abstract We report a case of a nine-year-old boy with a 4-week history of general fatigue, loss of appetite, vomits and hematemesis. Laboratory evaluation revealed a hemoglobin level of 4.4 g/dl. After a transfusion of packed red blood cells the patient underwent an esophagogastroduodenoscopy, which showed a smooth, rounded 6–8 cm submucosal lesion with a central depression with ulceration and active bleeding in the cardia extending to the fundus. Computed tomography (CT) of the chest, abdomen and pelvis showed a large mass originating from the gastric wall but not infiltrating surrounding organs, approximately 8.0 cm × 7.0 cm × 5 cm. Despite the tumor size, no metastases were diagnosed. The patient underwent a total gastrectomy in an en-bloc resection including the distal part of the esophagus (3 cm) and omentum with oncologic margins. Reconstruction was performed with a mediastinal end-to-side esophago-jejunal anastomosis. Immunehistochemic confirmed GIST. He remains well without evidence of disease after 36 months of follow-up with a multiprofessional team.