Allelic frequency distributions of 21 non-combined DNA index system STR loci in a Russian ethnic minority group from Inner Mongolia,China

We studied the allelic frequency distributions and statistical forensic parameters of 21 new short tandem repeat（STR）loci and the amelogenin locus,which are not included in the combined DNA index system（CODIS）,in a Russian ethnic minority group from the Inner Mongolia Autonomous Region,China.A total...

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Bibliographic Details
Published inJournal of Zhejiang University. B. Science Vol. 14; no. 6; pp. 533 - 540
Main Authors Wang, Hong-dan, Shen, Chun-mei, Liu, Wen-juan, Zhang, Yu-dang, Yang, Guang, Yan, Jiang-wei, Qin, Hai-xia, Zhu, Bo-feng
Format Journal Article
LanguageEnglish
Published Heidelberg SP Zhejiang University Press 01.06.2013
Springer Nature B.V
Zhejiang University Press
Subjects
Adolescent
Adult
Aged
Amelogenin - genetics
Biomedical and Life Sciences
Biomedicine
China - ethnology
Databases, Genetic
DNA Fingerprinting - methods
Female
Forensic Genetics - methods
Gene Frequency - genetics
Genetic Markers - genetics
Genetics, Population
Humans
Male
Microsatellite Repeats - genetics
Middle Aged
Minority Groups - statistics & numerical data
Russia - ethnology
Young Adult
China
Russia
Short tandem repeat (STR)
Russian population
Q39
Genetic polymorphisms
Online AccessGet full text
ISSN1673-1581
1862-1783
1862-1783
DOI10.1631/jzus.B1200262

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Summary:We studied the allelic frequency distributions and statistical forensic parameters of 21 new short tandem repeat（STR）loci and the amelogenin locus,which are not included in the combined DNA index system（CODIS）,in a Russian ethnic minority group from the Inner Mongolia Autonomous Region,China.A total of 114 bloodstain samples from unrelated individuals were extracted and co-amplified with four fluorescence-labeled primers in a multiplex polymerase chain reaction（PCR）system.Using capillary electrophoresis,the PCR products of the 21 STR loci were separated and genotyped.A total of 161 alleles were observed in the Russian ethnic minority group,and corresponding allelic frequencies ranged from 0.0044 to 0.5965.The 21 non-CODIS STR loci of the Russian ethnic minority group were characterized by high genetic diversity and therefore may be useful for elucidating the population’s genetic background,for individual identification,and for paternity testing in forensic practice.
Bibliography:We studied the allelic frequency distributions and statistical forensic parameters of 21 new short tandem repeat（STR）loci and the amelogenin locus,which are not included in the combined DNA index system（CODIS）,in a Russian ethnic minority group from the Inner Mongolia Autonomous Region,China.A total of 114 bloodstain samples from unrelated individuals were extracted and co-amplified with four fluorescence-labeled primers in a multiplex polymerase chain reaction（PCR）system.Using capillary electrophoresis,the PCR products of the 21 STR loci were separated and genotyped.A total of 161 alleles were observed in the Russian ethnic minority group,and corresponding allelic frequencies ranged from 0.0044 to 0.5965.The 21 non-CODIS STR loci of the Russian ethnic minority group were characterized by high genetic diversity and therefore may be useful for elucidating the population’s genetic background,for individual identification,and for paternity testing in forensic practice.
33-1356/Q
Short tandem repeat（STR）； Russian population； Genetic polymorphisms
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Corresponding Author
ISSN:1673-1581
1862-1783
1862-1783
DOI:10.1631/jzus.B1200262