Best-Evidence Interventions: Findings From a Systematic Review of HIV Behavioral Interventions for US Populations at High Risk, 2000-2004

The Centers for Disease Control and Prevention's HIV/AIDS Prevention Research Synthesis Team conducted a systematic review of US-based HIV behavioral intervention research literature from 2000 through 2004 to identify interventions demonstrating best evidence of efficacy for reducing HIV risk....

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Published inAmerican journal of public health (1971) Vol. 97; no. 1; pp. 133 - 143
Main Authors Lyles, Cynthia M, Kay, Linda S, Crepaz, Nicole, Herbst, Jeffrey H, Passin, Warren F, Kim, Angela S, Rama, Sima M, Thadiparthi, Sekhar, DeLuca, Julia B, Mullins, Mary M, Hiv/aids Prevention Research Synthesis Team
Format Journal Article
LanguageEnglish
Published Washington, DC Am Public Health Assoc 01.01.2007
American Public Health Association
American Journal of Public Health 2007
Subjects
Acquired immune deficiency syndrome
AIDS
Behavior
Biological and medical sciences
Disease control
Disease prevention
Evidence-Based Medicine
Exchange programs
Health Promotion - methods
HIV
HIV Infections - prevention & control
HIV Infections - psychology
Human immunodeficiency virus
Human viral diseases
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infections
Infectious diseases
Intervention
Medical sciences
Miscellaneous
Prevention programs
Public health
Public health. Hygiene
Public health. Hygiene-occupational medicine
Research and Practice
Risk Reduction Behavior
Sexual Behavior
Sexually Transmitted Diseases - prevention & control
Sexually Transmitted Diseases - psychology
States
Strategic planning
Studies
Systematic review
Treatment Outcome
United States
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
USA
Infection
Human
Immunopathology
Viral disease
Evidence-based practice
Systematic review
AIDS
Behavior
Risk taking
Immune deficiency
Public health
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Summary:The Centers for Disease Control and Prevention's HIV/AIDS Prevention Research Synthesis Team conducted a systematic review of US-based HIV behavioral intervention research literature from 2000 through 2004 to identify interventions demonstrating best evidence of efficacy for reducing HIV risk. Standard systematic review methods were used. Each eligible study was reviewed on the basis of Prevention Research Synthesis Team efficacy criteria that focused on 3 domains: study design, implementation and analysis, and strength of evidence. Eighteen interventions met the criteria for best evidence. Four targeted HIV-positive individuals. Of those targeting populations at risk for HIV, 4 targeted drug users, 6 targeted adults at risk because of heterosexual behaviors only, 2 targeted men who have sex with men, and 2 targeted youths at high risk. Eight interventions focused on women, and 13 had study samples with more than 50% minority participants. Significant intervention effects included increased condom use and reductions in unprotected sexual intercourse, number of sexual partners, injection drug use or needle sharing, and newly acquired sexually transmitted infections. Most of the best-evidence interventions are directly applicable for populations in greatest need of effective prevention programs; however, important gaps still exist.
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Requests for reprints should be sent to Cynthia M. Lyles, Prevention Research Branch, Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E–37, Atlanta, GA 30333 (e-mail: clyles@cdc.gov).
Peer Reviewed
Note. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention.
Contributors…C. M. Lyles led the writing, abstracted data, and reviewed studies for evidence of efficacy. L. S. Kay, N. Crepaz, and J. H. Herbst helped with writing, abstracted data, and reviewed studies for evidence of efficacy. W.F. Passin, A. S. Kim, and S. M. Rama conducted most of the data abstraction and qualitative data coding from the original evaluation reports and reviewed studies for evidence of efficacy. S. Thadiparthi developed and managed the database used to summarize the data. J. B. DeLuca and M. M. Mullins led the systematic search efforts to identify all relevant evaluation studies.
ISSN:0090-0036
1541-0048
DOI:10.2105/AJPH.2005.076182