Biosynthesis and antibacterial activity of MgO-NPs produced from Camellia-sinensis leaves extract

• Published in: Materials research express Vol. 8; no. 1; pp. 15402 - 15411
• Main Authors: Khan, Abdulhameed, Shabir, Dania, Ahmad, Pervaiz, Khandaker, Mayeen Uddin, Faruque, M R I, Din, Israf Ud
• Format: Journal Article
• Language: English
• Published: Bristol IOP Publishing 01.01.2021
• Subjects: antibacterial-activity; Antibiotics; Bacteria; Biosynthesis; Camellia-sinensis; E coli; Green tea; Green-Synthesis; Klebsiella; Magnesium oxide; Nanoparticles; Pseudomonas aeruginosa; Superconductors (materials)
• ISSN: 2053-1591; 2053-1591
• DOI: 10.1088/2053-1591/abd421

Magnesium oxides nanoparticles (MgO-NPs) were synthesized by a novel technique based on the leaf extract of Camellia sinensis (Green tea). The synthesized nanoparticles were evaluated for antibacterial activity (against both gram-positive and gram-negative pathogens) and therefore can be a suitable therapeutic alternative to the usage of antibiotics. The antibacterial activity of synthesized MgO-NPs is tested against clinical isolates of gram-negative (Escherichia coli, Pseudomonas aeruginosa, Serratia mercescens, Klebsiella pneumoniae) and gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes) pathogenic bacteria. Agar well diffusion assay data indicate that MgO-NPs exhibit antibacterial activity at all concentrations tested against both gram-negative and gram-positive pathogenic bacteria, producing zone of inhibition (ZOI) in the range of 9.6 1.1 to 21.0 1.5 mm diameters. The maximum response is observed at 25 g ml−1 concentration of MgO-NPs, producing a zone of inhibition ranging from 15 1.2 mm (E.coli) mm to 21.0 1.5 mm (S. marcescens).