Development of Acute Inflammatory Demyelinating Polyneuropathy 11 Days after Spinal Surgery: A Case Report and Literature Review

Guillain–Barré syndrome (GBS) usually has a good prognosis; however, patients may develop sequelae without prompt treatment. We herein describe an 81-year-old woman who developed acute-onset excruciating thigh pain and weakness in her lower extremities after spinal surgery. We diagnosed acute inflam...

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Published inCase reports in medicine Vol. 2021; pp. 1 - 9
Main Authors Kakehi, Eiichi, Kawakami, Tadataka, Ishikawa, Yukiko, Matsuoka, Takashi, Nakagawa, Naoki, Morishita, Tugutake, Taniguchi, Shohei, Akamatsu, Yukinobu, Sakurai, Shigehisa, Hirotani, Akane, Nozaki, Takafumi, Shoji, Keisuke, Adachi, Seiji, Kotani, Kazuhiko, Matsumura, Masami
Format Journal Article
LanguageEnglish
Published New York Hindawi 28.07.2021
Hindawi Limited
Wiley
Subjects
Autonomic nervous system
Back surgery
Case Report
Case reports
Cerebrospinal fluid
Complications
Demyelination
Guillain-Barre syndrome
Health aspects
Inflammation
Literature reviews
Magnetic resonance imaging
Medical research
Muscle strength
Nerve conduction
Neuropathy
Orthopedic surgery
Pain
Patients
Polyneuropathy
Prognosis
Respiratory failure
Spinal cord
Spinal stenosis
Surgery
Surgical outcomes
Tendons
Japan
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Summary:Guillain–Barré syndrome (GBS) usually has a good prognosis; however, patients may develop sequelae without prompt treatment. We herein describe an 81-year-old woman who developed acute-onset excruciating thigh pain and weakness in her lower extremities after spinal surgery. We diagnosed acute inflammatory demyelinating polyradiculoneuropathy by a nerve conduction study, which showed findings of demyelination without cerebrospinal fluid analysis because of a spinal prosthesis. Although anti-GM1 and anti-GalNAc-GD1a antibodies were positive, the patient was clinically diagnosed with acute inflammatory demyelinating polyradiculoneuropathy (a subtype of GBS), not acute motor axonal neuropathy. She recovered well with immunoglobulin therapy. A literature review of 18 cases revealed that unexplained weakness, areflexia, and numbness of the extremities after spinal surgery, a shorter time from spinal surgery to symptom onset to general GBS, abnormal nerve conduction study results, normal spinal imaging findings, and the development of atypical symptoms such as cranial and autonomic nerve syndrome and respiratory failure are useful for diagnosing GBS when cerebrospinal fluid examination cannot be performed after spinal surgery.
Bibliography:Academic Editor: Mamede de Carvalho
ISSN:1687-9627
1687-9635
DOI:10.1155/2021/6283076