Exploiting Circular DNA

The properties of circular DNA provide an important tool for the investigation of the double helix and its interactions with ligands and proteins. Vologodskii comments on a study by Zeman et al, in which they have developed a new method to study DNA-ligand complexes.

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Bibliographic Details
Published inProceedings of the National Academy of Sciences - PNAS Vol. 95; no. 8; pp. 4092 - 4093
Main Author Vologodskii, Alexander
Format Journal Article
LanguageEnglish
Published United States National Academy of Sciences of the United States of America 14.04.1998
National Acad Sciences
National Academy of Sciences
The National Academy of Sciences
Subjects
Base Composition
Biochemistry
Bromides
Circular DNA
Commentary
Deoxyribonucleic acid
DNA
DNA, Circular - chemistry
DNA, Circular - metabolism
Electrophoresis
Experimental data
Gels
Genetic equilibrium
Ligands
Models, Chemical
Molecules
Nucleic Acid Conformation
Plasmids - chemistry
Plasmids - metabolism
Proteins
Topology
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Summary:The properties of circular DNA provide an important tool for the investigation of the double helix and its interactions with ligands and proteins. Vologodskii comments on a study by Zeman et al, in which they have developed a new method to study DNA-ligand complexes.
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ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.95.8.4092