Presentation and initial assessment of ENT problems in patients with granulomatosis with polyangiitis (Wegener's)
Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area. To highlight salient features...
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| Published in | Journal of laryngology and otology Vol. 128; no. 8; pp. 730 - 737 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge, UK
Cambridge University Press
01.08.2014
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area.
To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition.
A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described.
Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis.
The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis. |
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| AbstractList | Abstract
Background:
Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area.
Objective:
To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition.
Methods:
A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described.
Results:
Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis.
Conclusion:
The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis. Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area. To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition. A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described. Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis. The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis. BACKGROUNDGranulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area.OBJECTIVETo highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition.METHODSA case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described.RESULTSEighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis.CONCLUSIONThe time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis. Abstract Background: Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area. Objective: To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition. Methods: A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described. Results: Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis. Conclusion: The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis. |
| Author | Martinez Del Pero, M McKiernan, D Jani, P |
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fullname: Helmberger – volume: 15 start-page: 673 year: 1982 ident: S0022215114001492_ref49 article-title: Wegener's granulomatosis publication-title: Otolaryngol Clin North Am doi: 10.1016/S0030-6665(20)32156-3 contributor: fullname: Kornblut – ident: S0022215114001492_ref41 doi: 10.1007/s004050100327 – volume: 48 start-page: 2299 year: 2003 ident: S0022215114001492_ref47 article-title: Limited versus severe Wegener's granulomatosis: baseline data on patients in the Wegener's granulomatosis etanercept trial publication-title: Arthritis Rheum doi: 10.1002/art.11075 contributor: fullname: Stone – ident: S0022215114001492_ref46 doi: 10.1288/00005537-198009000-00005 – volume: 30 start-page: 2070 year: 2003 ident: S0022215114001492_ref63 article-title: Cranial pachymeningitis: an unusual manifestation of Wegener's granulomatosis publication-title: J Rheumatol contributor: fullname: Fam – ident: S0022215114001492_ref71 doi: 10.1309/WAEPADW0K4LPUHFN – ident: S0022215114001492_ref35 doi: 10.1017/S0022215100089362 – ident: S0022215114001492_ref79 doi: 10.1007/s00234-002-0885-9 – ident: S0022215114001492_ref7 doi: 10.1056/NEJM198806233182504 |
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| Snippet | Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels... Abstract Background: Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to... Abstract Background: Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to... BACKGROUNDGranulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized... |
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| SubjectTerms | Adult Algorithms Biopsy Clinical Records Ear Diseases - diagnosis Ears & hearing Female Granulomatosis with Polyangiitis - diagnosis Granulomatosis with Polyangiitis - therapy Hearing loss Humans Inflammation Neutrophils Nose Nose Diseases - diagnosis Pharyngeal Diseases - diagnosis Remission (Medicine) Rheumatology Serology |
| Title | Presentation and initial assessment of ENT problems in patients with granulomatosis with polyangiitis (Wegener's) |
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