Presentation and initial assessment of ENT problems in patients with granulomatosis with polyangiitis (Wegener's)

• Published in: Journal of laryngology and otology Vol. 128; no. 8; pp. 730 - 737
• Main Authors: Martinez Del Pero, M, McKiernan, D, Jani, P
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.08.2014
• Subjects: Adult; Algorithms; Biopsy; Clinical Records; Ear Diseases - diagnosis; Ears & hearing; Female; Granulomatosis with Polyangiitis - diagnosis; Granulomatosis with Polyangiitis - therapy; Hearing loss; Humans; Inflammation; Neutrophils; Nose; Nose Diseases - diagnosis; Pharyngeal Diseases - diagnosis; Remission (Medicine); Rheumatology; Serology; Antibodies, Antineutrophil Cytoplasmic; Wegener Granulomatosis; Vasculitis; Diagnosis
• ISSN: 0022-2151; 1748-5460
• DOI: 10.1017/S0022215114001492

Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area. To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition. A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described. Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis. The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis.