Freeze-Casting of Porous Biomaterials: Structure, Properties and Opportunities

The freeze-casting of porous materials has received a great deal of attention during the past few years. This simple process, where a material suspension is simply frozen and then sublimated, provides materials with unique porous architectures, where the porosity is almost a direct replica of the fr...

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Bibliographic Details
Published inMaterials Vol. 3; no. 3; pp. 1913 - 1927
Main Author Deville, Sylvain
Format Journal Article Book Review
LanguageEnglish
Published Basel MDPI AG 01.03.2010
MDPI
Molecular Diversity Preservation International
Subjects
biomaterials
Chemical Sciences
composites
Engineering Sciences
freeze-casting
Material chemistry
Materials
porous ceramics
Review
composites
freeze-casting
biomaterials
porous ceramics
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Summary:The freeze-casting of porous materials has received a great deal of attention during the past few years. This simple process, where a material suspension is simply frozen and then sublimated, provides materials with unique porous architectures, where the porosity is almost a direct replica of the frozen solvent crystals. This review focuses on the recent results on the process and the derived porous structures with regards to the biomaterials applications. Of particular interest is the architecture of the materials and the versatility of the process, which can be readily controlled and applied to biomaterials applications. A careful control of the starting formulation and processing conditions is required to control the integrity of the structure and resulting properties. Further in vitro and in vivo investigations are required to validate the potential of this new class of porous materials.
ISSN:1996-1944
1996-1944
DOI:10.3390/ma3031913