Association Between Leukocyte Telomere Length and Drug-Eluting Stent Strut Coverage by Optical Coherence Tomography

• Published in: Journal of the American College of Cardiology Vol. 59; no. 24; pp. 2218 - 2219
• Main Authors: Armstrong, Ehrin J., MD, Xing, Lei, MD, Zhang, Jianzhong, MD, PhD, Zheng, Yanhua, PhD, Shunk, Kendrick A., MD, PhD, Yeh, Robert W., MD, Farzaneh-Far, Ramin, MD, Yu, Bo, MD, PhD, Jang, Ik-Kyung, MD, PhD
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 12.06.2012; Elsevier; Elsevier Limited
• Subjects: Aged; Angioplasty; Biological and medical sciences; Bone marrow; Cardiology; Cardiology. Vascular system; Cardiovascular; Coronary Angiography; Coronary Restenosis - diagnosis; Coronary vessels; Drug-Eluting Stents; Female; Humans; Internal Medicine; Leukocytes - cytology; Male; Medical sciences; Middle Aged; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Stents; Telomere - physiology; Tomography, Optical Coherence; Veins & arteries; Association; Optical coherence tomography; Leukocyte; Length; Instrumentation therapy; Coverage; Circulatory system; Cardiology; Drug eluting stent; Telomere
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2012.03.028

Continuous variables are presented as median (interquartile range [IQR]) and categorical variables as percents or counts. Because telomere length was not normally distributed, all analyses were performed using log-transformed data. There was also a nonsignificant trend between LTL and mean neointimal coverage (R2 = 0.28, p = 0.20). Because LTL is inversely correlated with age, we also examined the association of LTL and stent strut coverage, adjusted for age.