Factors associated with tuberculosis and multidrug-resistant tuberculosis in patients treated at a tertiary referral hospital in the state of Minas Gerais, Brazil

• Published in: Jornal brasileiro de pneumologia Vol. 46; no. 2; p. e20180386
• Main Authors: Soares, Valéria Martins, Almeida, Isabela Neves de, Figueredo, Lida Jouca de Assis, Haddad, João Paulo Amaral, Oliveira, Camila Stefanie Fonseca de, Carvalho, Wânia da Silva, Miranda, Silvana Spindola de
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Sociedade Brasileira de Pneumologia e Tisiologia 2020
• Subjects: Original; RESPIRATORY SYSTEM; Risk factors; Tuberculosis; Tuberculosis, multidrug-resistant; Tuberculosis, multidrug-resistant; Tuberculosis; Tuberculose; Fatores de risco; Tuberculose resistente a múltiplos medicamentos; Risk factors
• ISSN: 1806-3756; 1806-3713; 1806-3756
• DOI: 10.36416/1806-3756/e20180386

To evaluate the risk factors for the development of tuberculosis and multidrug-resistant tuberculosis (MDR-TB) in patients treated at a tertiary referral hospital. This was a cross-sectional study based on data obtained from patients treated at the Júlia Kubitschek Hospital, located in the city of Belo Horizonte, Brazil, between October of 2012 and October of 2014. We evaluated sociodemographic, behavioral, clinical, and radiological variables. The outcome considered to identify associations between tuberculosis and the explanatory variables was the treatment prescribed. To evaluate the associations between MDR-TB and the same explanatory variables, the change in MDR-TB treatment was considered. The factors associated with tuberculosis were alcoholism, comorbidities, pulmonary cavitations, and a radiological pattern suggestive of tuberculosis. Cavitation and previous treatment for tuberculosis were associated with MDR-TB. Despite the significant progress made in the fight against tuberculosis, there is a need for coordinated actions that include social protection measures and patient support.