Remineralization of early enamel lesions using casein phosphopeptide amorphous calcium Phosphate: An ex-vivo study

• Published in: Contemporary clinical dentistry Vol. 1; no. 4; pp. 210 - 213
• Main Authors: Vashisht, Ruchi, Kumar, Anil, Indira, R, Srinivasan, MR, Ramachandran, S
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.10.2010; Medknow Publications & Media Pvt. Ltd; Medknow Publications Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Care and treatment; Casein; casein-phosphopeptide amorphous calcium phosphate; Enamel; Enamel remineralisation; Enamel, Dental; Hydroxyapatite; Original; Physiological aspects; Properties; Studies; Teeth; India; Enamel remineralisation; casein-phosphopeptide amorphous calcium phosphate
• ISSN: 0976-237X; 0976-2361; 0976-2361
• DOI: 10.4103/0976-237X.76385

This study aimed at qualitatively evaluating the remineralization potential of casein phosphopeptide amorphous calcium phosphate on artificial early enamel lesions in an ex-vivo scenario by observing the treated tooth surface using a scanning electron microscope (SEM). This randomized study was conducted on 10 subjects undergoing orthodontic treatment with premolar extraction as part of their treatment. Artificial white lesions were created with the application of 37% phosphoric acid for 20 mins. Teeth were then divided into two groups: one experimental and the other control. Customised orthodontic band with a window was luted with intermediate restorative material in the experimental group whereas in the control group, band without a window was luted. The casein phosphopeptide amorphous calcium phosphate (GC TOOTH MOUSSE) paste was then applied on the window region of the experimental group for 3 mins thrice daily after meals for 14 days, whereas no paste was applied in the control group. After 14 days, teeth were extracted and viewed under an SEM. The study groups showed remineralization of the lesions as compared with the control group in most of the samples. Casein phophopeptide could significantly remineralize the artificial enamel lesions in vivo.