The role of oxygen in cluster headache

High-flow oxygen inhalation is one of the most effective acute treatments for cluster headache. The therapy was first described for the treatment of cluster headache in 1952 by Horton, and has exhibited some advantages and efficacy compared to other acute medicines. The mechanism is not very clear,...

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Published inMedical gas research Vol. 9; no. 4; pp. 229 - 231
Main Authors Guo, Xiao-Ning, Lu, Jia-Jie, Ni, Jian-Qiang, Lu, Hai-Feng, Zhao, Hong-Ru, Chen, Gang
Format Journal Article
LanguageEnglish
Published Australia Wolters Kluwer India Pvt. Ltd 01.10.2019
Medknow Publications & Media Pvt. Ltd
Wolters Kluwer - Medknow
Subjects
Cluster Headache - pathology
Cluster Headache - therapy
Headaches
Histamine
Humans
Hyperbaric Oxygenation
Hyperoxia
Hypothalamus - metabolism
Oxygen - metabolism
Oxygen therapy
Review
Studies
Tryptamines - therapeutic use
clinical research
experimental research
acute treatment
cluster headache
pathophysiology
primary headache
hyperbaric oxygen
oxygen
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Summary:High-flow oxygen inhalation is one of the most effective acute treatments for cluster headache. The therapy was first described for the treatment of cluster headache in 1952 by Horton, and has exhibited some advantages and efficacy compared to other acute medicines. The mechanism is not very clear, but some evidence has demonstrated its relationship to the trigeminovascular system and neuroinflammation. High-flow oxygen inhalation via a non-rebreather mask during cluster headache attacks has been widely recommended. Patients with frequent attacks and/or intolerance to drugs may prefer the oxygen treatment.
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Manuscript writing: XNG and JJL; manuscript revision: JQN and HFL; manuscript drafting and revision: HRZ and GC. All the authors read and approved the final version of the manuscript for publication.
These authors contributed equally to this work.
Author contributions
ISSN:2045-9912
2045-9912
DOI:10.4103/2045-9912.273961