Cortical excitability varies upon ictal onset patterns in neocortical epilepsy: A cortico-cortical evoked potential study

• Published in: Clinical neurophysiology Vol. 123; no. 2; pp. 252 - 260
• Main Authors: Enatsu, Rei, Piao, Zhe, O’Connor, Timothy, Horning, Karl, Mosher, John, Burgess, Richard, Bingaman, William, Nair, Dileep
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ireland Ltd 01.02.2012; Elsevier
• Subjects: Action Potentials - physiology; Adolescent; Adult; Biological and medical sciences; Child; Cortical stimulation; Electric Stimulation - methods; Electrocorticography; Electrodiagnosis. Electric activity recording; Electroencephalography - methods; Epilepsy; Epilepsy - diagnosis; Epilepsy - physiopathology; Evoked potential; Evoked Potentials - physiology; Female; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Ictal onset; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Neocortex - physiopathology; Nervous system; Nervous system (semeiology, syndromes); Neurology; Young Adult; Cortical stimulation; Evoked potential; Ictal onset; Epilepsy; Electrocorticography; Human; Nervous system diseases; Cerebral cortex; Electrical stimulus; Central nervous system; Electrophysiology; Excitability; Stimulus intensity; Encephalon; Cerebral disorder; Electrodes; Electrodiagnosis; Central nervous system disease; Repetitive stimulus; Excitation; Monitoring
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2011.06.030

Highlights ► This study confirms in a new way that cortical excitability varies depending on the ictal onset patterns seen on electrocorticography. ► This is a cortico-cortical evoked potential (CCEP) study to evaluate pathological neuronal excitation in ictal onset regions with different ictal onset patterns. ► This is the first report to evaluate pro-epileptic excitability in regions showing different ictal onset patterns and is useful to better understand pathological neuronal excitation in epilepsy.