Italian Clinical Practice Guidelines on Cholangiocarcinoma – Part II: Treatment

Currently, the only curative treatment for cholangiocarcinoma (CCA) is surgical resection, though this treatment is possible in less than 40% of patients. However, recent improvements in preoperative management have led to a higher number of patients who are candidates for this procedure. For unrese...

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Published inDigestive and liver disease Vol. 52; no. 12; pp. 1430 - 1442
Main Authors Alvaro, Domenico, Hassan, Cesare, Cardinale, Vincenzo, Carpino, Guido, Fabris, Luca, Gringeri, Enrico, Granata, Vincenza, Mutignani, Massimiliano, Morement, Helen, Giuliante, Felice, Guglielmi, Alfredo, Ridola, Lorenzo, Tonini, Giuseppe, Marzioni, Marco, Grazi, Gianluca, Guido, Maria, Di Giulio, Emilio, Pantano, Francesco, Venere, Rosanna, Bragazzi, Maria Consiglia, Biancanello, Francesca, Faccioli, Jessica, Giannetti, Aurora, Cintolo, Marcello, Di Giunta, Michela, Gambato, Martina, Lasagni, Alberto, Izzo, Francesco, Avallone, Antonio, Banales, Jesus, Rossi, Massimo, Catalano, Carlo, Laghi, Andrea, D'amati, Giulia, Mancino, Maria Grazia
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.12.2020
Subjects
Distal cholangiocarcinoma
Intrahepatic cholangiocarcinoma
Liver transplantation
Locoregional treatments
Perihilar cholangiocarcinoma
Surgery
Target therapies
Surgery
Intrahepatic cholangiocarcinoma
Locoregional treatments
Perihilar cholangiocarcinoma
Distal cholangiocarcinoma
Target therapies
Liver transplantation
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Summary:Currently, the only curative treatment for cholangiocarcinoma (CCA) is surgical resection, though this treatment is possible in less than 40% of patients. However, recent improvements in preoperative management have led to a higher number of patients who are candidates for this procedure. For unresectable patients, progress is ongoing in terms of locoregional and chemoradiation treatments and target therapies, especially in the definition of patient selection criteria. This is the second part of the Italian CCA guidelines, dealing with CCA treatment, that have been formulated in accordance with Italian National Institute of Health indications and developed according to the GRADE method and related advancements.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Instructional Material/Guideline-3
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ISSN:1590-8658
1878-3562
1878-3562
DOI:10.1016/j.dld.2020.08.030