Smoking cessation in patients requiring bronchoscopy: The Bronchoscopy AntiSmoking Study (BASIS)

• Published in: Respiratory medicine Vol. 104; no. 1; pp. 61 - 66
• Main Authors: Martucci, Paola, Sestini, Piersante, Canessa, Pier Aldo, Brancaccio, Luigi, Guarino, Carmen, Barbato, Natalino, Lodi, Marco, Coloretti, Isotta, Del Donno, Mario, Sini, Albino, Cinti, Cristina, Melani, Andrea S
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.01.2010; Elsevier; Elsevier Limited
• Subjects: Addictions; Biological and medical sciences; Bronchoscopy; Bronchoscopy - psychology; Counseling; Female; Hospitalization; Humans; Intervention; Male; Medical sciences; Middle Aged; Mortality; Nicotine; Nicotine dependence; Patient Acceptance of Health Care - psychology; Patient Education as Topic; Personal relationships; Pneumology; Pulmonary/Respiratory; Quitting rate; Smoking - psychology; Smoking cessation; Smoking Cessation - methods; Smoking Cessation - psychology; Smoking cessation advice; Surveys and Questionnaires; Tobacco, tobacco smoking; Toxicology; Treatment Outcome; Smoking cessation advice; Bronchoscopy; Quitting rate; Nicotine dependence; Human; Tobacco smoking; Endoscopy; Pneumology
• ISSN: 0954-6111; 1532-3064
• DOI: 10.1016/j.rmed.2009.08.002

Summary We investigated the readiness to quit and the smoking cessation rates of smokers requring bronchoscopy and receiving advice quitting. This randomized controlled trial evaluated the effectiveness of two smoking cessation interventions, either a brief advice (control group), or a longer support, delivered at the time of bronchoscopy. We consecutively enrolled 233 adult smokers, regardless of the initial level of motivation to quit. Their mean (SD) age was 57 (12) years; males were 192. They had smoked a median of 44.5 pack-years. Their mean (SD) Fagerstrom score was 8 (2). There was no difference between groups. Surprisingly, 45% of participants were in the action stage at baseline; these 105 subjects had quit in the week immediately prior to the bronchoscopy. At 6- and 12-months follow-up visits, respectively 41% and 29% of participants in the intervention group and 27% and 13% in the control group objectively showed a 1-week point prevalence abstinence. The difference was significant at 6 months ( p < 0.05) but not at 1-year visit ( p = 0.052), even if there was a trend towards greater cessation rate in the intervention group. In multivariable logistic models, at the final visit being a quitter was positively associated with having been in the action stage at baseline and negatively with the Fagerstrom score and the presence of smokers in household. We conclude that the time of bronchoscopy may possibly predispose smokers to quit. Further efforts are needed to clear whether more protracted support might achieve higher long-term smoking cessation rates.