Multivisceral systemic metastases from an intracranial anaplastic meningioma: A case report and review of literature

• Published in: Clinical neurology and neurosurgery Vol. 113; no. 7; pp. 592 - 595
• Main Authors: Lambertz, N, Koehler, J, Schulte, D.M, Kuehl, H, Wohlschlaeger, J, Hense, J, Schuler, M, Mueller, O.M
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.09.2011; Elsevier; Elsevier Limited
• Subjects: Aged; Aggressiveness; Antineoplastic Agents - therapeutic use; Biological and medical sciences; Biopsy; Brain Neoplasms - pathology; Brain Neoplasms - surgery; Cancer; Carcinoma - pathology; Carcinoma - surgery; Chemotherapy; Fatal Outcome; Female; Humans; Hydroxyurea - therapeutic use; Liver; Liver Neoplasms - secondary; Lung; Lung Neoplasms - secondary; Magnetic Resonance Imaging; Medical sciences; Meningioma; Meningioma - pathology; Metastases; Neoplasm Metastasis - pathology; Neurology; Neurosurgery; Radiography, Thoracic; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tomography, X-Ray Computed; Tumors; Chemotherapy; Lung; Liver; Meningioma; Metastases; Intracranial; Nervous system diseases; Malignant tumor; Metastasis; Case study; Treatment; Surgery; Benign neoplasm; Cancer
• ISSN: 0303-8467; 1872-6968
• DOI: 10.1016/j.clineuro.2011.02.017

Overall, metastases are more likely in recurrent tumors and seem to be rare in primary tumors [10,12,15,16]. [...]the risk of metastatic spread apparently depends on the histological tumor grade, being higher in high WHO grade meningiomas. Due to the scarce data it remains unclear, whether selected high risk patients might benefit from adjuvant radio- or chemoradiotherapy. [...]clinical studies of systemic therapy of this relatively rare disease are required.