Conversion of citric acid to itaconic acid in a novel liquid membrane bioreactor
A novel liquid membrane reactor was designed to carry out the conversion of citric acid to itaconic (methylene succinic) acid by the fungus Aspergillus terreus. This bioreactor contained two supported liquid membranes (SLMs) that divided it into three compartments: (1) the feed chamber containing ci...
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Published in | Journal of chemical technology and biotechnology (1986) Vol. 75; no. 1; pp. 66 - 72 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Chichester, UK
John Wiley & Sons, Ltd
01.01.2000
Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | A novel liquid membrane reactor was designed to carry out the conversion of citric acid to itaconic (methylene succinic) acid by the fungus Aspergillus terreus. This bioreactor contained two supported liquid membranes (SLMs) that divided it into three compartments: (1) the feed chamber containing citric acid; (2) the reaction chamber containing the enzyme A terreus cells; and (3) the product collection chamber containing the counter‐ion. The specificity of SLMs allows the unidirectional flow, of the substrate from the feed to the reaction chamber, and of the product from the reaction to the product chamber in exchange for a counter‐ion, thus maintaining low concentrations of both the product and the substrate, and limiting their inhibitory effects on the conversion process. The yield of itaconic acid in the membrane bioreactor was about two orders of magnitude higher than in the batch process.
© 2000 Society of Chemical Industry |
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Bibliography: | Levi Eshkol Foundation, The Ministry of Science of the State of Israel istex:D7D5286115126C6A4D3E4862FDFED3DF9D495D8F ArticleID:JCTB176 ark:/67375/WNG-N10SN1FV-Z ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 0268-2575 1097-4660 |
DOI: | 10.1002/(SICI)1097-4660(200001)75:1<66::AID-JCTB176>3.0.CO;2-U |