Meary angle for the prediction of mitral valve prolapse risk in non-syndromic patients with pes planus, a cross-sectional study

• Published in: BMC research notes Vol. 15; no. 1; p. 145
• Main Authors: AbdelMassih, Antoine, Hozaien, Rafeef, Mishriky, Fady, Michael, Mark, AmanAllah, Mostafa, Ali, Nada, ElGamal, Nadine, Medhat, Omar, Kamel, Mona, Helmy, Rasha, Sarhan, Mai, Attalla, Hams, Dawoud, Omneya, Marwan, Athar, Ghobashy, Mohamed
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 25.04.2022; BioMed Central; BMC
• Subjects: Accuracy; Child; Complications and side effects; Congenital diseases; Connective tissue; Cross-Sectional Studies; Echocardiography; Feet; Flatfoot; Flatfoot - complications; Foot diseases; Humans; Investigations; Marfan syndrome; Meary angle; Mitral valve; Mitral Valve - diagnostic imaging; Mitral valve prolapse; Mitral Valve Prolapse - complications; Mitral Valve Prolapse - diagnostic imaging; Mitral Valve Prolapse - epidemiology; Mutation; MVP; Pediatric research; Pes planus; Research Note; Risk factors; Statistics; Egypt; Pes planus; Meary angle; MVP
• ISSN: 1756-0500; 1756-0500
• DOI: 10.1186/s13104-022-06032-0

Mitral Valve Prolapse (MVP) is a common valvular abnormality accounting for 2% of the population. There is a reported association between pes planus (PP) and MVP in some syndromes such as Marfan. However, this association has not been tested in non-syndromic cases. The primary outcome of this study is to measure the prevalence of MVP in a population of patients with PP. The secondary outcome parameter is to determine if the Meary angle (MA), a measure of the severity of flat foot, can be effectively used in the prediction of the presence of MVP. Forty-one patients with PP were screened using a lateral x-ray foot to determine MA while echocardiography was utilized to identify the presence and grade of MVP. 88% of screened patients were diagnosed with MVP. MA was correlated with the grade of MVP and showed high diagnostic accuracy (sensitivity 100% and specificity 90%) in predicting MVP risk when higher than 5. Children with PP are at a higher risk for MVP than the general population. Accordingly, the utilization of MA in such a specific population for the determination of patients at a higher need for echocardiography seems to be a worthwhile strategy in diagnosing MVP.