Sex effects on the association between sarcopenia EWGSOP and osteoporosis in outpatient older adults: data from the SARCOS study

• Published in: Archives of Endocrinology and Metabolism Vol. 62; no. 6; pp. 615 - 622
• Main Authors: Frisoli, Jr, Alberto, Martin, Fabíola Giannattasio, Carvalho, Antonio Carlos de Camargo, Borges, Jairo, Paes, Angela T, Ingham, Sheila Jean McNeill
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Endocrinologia e Metabologia 01.12.2018; Brazilian Society of Endocrinology and Metabolism
• Subjects: Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Body Composition; Bone aging; Bone Density; Brazil - epidemiology; Cardiovascular Diseases - epidemiology; Cross-Sectional Studies; Disability Evaluation; Female; Hand Strength; Humans; Logistic Models; Male; muscle; Original; Osteoporosis - complications; Osteoporosis - epidemiology; Outpatients - statistics & numerical data; Prevalence; Prospective Studies; Risk Factors; Sarcopenia - complications; Sarcopenia - epidemiology; Sex Distribution; Sex Factors; Brazil
• ISSN: 2359-3997; 2359-4292; 2359-4292
• DOI: 10.20945/2359-3997000000087

The objective was to evaluate the association between sarcopenia (EWGSOP) and osteoporosis in older adults. This is a cross sectional analysis of a baseline evaluation of the SARCopenia and OSteoporosis in Older Adults with Cardiovascular Diseases Study (SARCOS). Three hundred and thirty-two subjects over 65 years of age were evaluated. Sarcopenia was determined by EWGSOP flowchart and Osteoporosis was established by WHO's criteria. Physical function, comorbidities and medications were evaluated. Women were older (79.8 ± 7.2 years) than men (78.21 ± 6.7 years) (p = 0.042). Osteoporosis occurred in 24.8% of men, and in 42.7% of women (p < 0.001); sarcopenia occurred in 25.5% of men and in 17.7%, of women (p = 0.103). Osteoporosis was diagnosed in 68% of sarcopenic women, however only 20.7% (p = 0.009) of women with osteoporosis had sarcopenia; in older men, 44.7% of individuals with sarcopenia presented osteoporosis and 42.9% (p = 0.013) of men with osteoporosis showed sarcopenia. In an adjusted logistic regression analyses for sarcopenia, osteoporosis presented a statistically significant association with sarcopenia in men [OR: 2.930 (95% CI: 1.044-8.237; p = 0.041)] but not in women [OR: 2.081 (0.787-5.5; p = 0.142)]; in the adjusted logistic regression analyses for osteoporosis, a statistically significant association occurred in men [OR: 2.984 (95% CI: 1.144-7.809; p = 0.025)], but not in women [OR: 2.093 (0.962-3.714; p = 0.137)]. According to sex, there are significant differences in the association between sarcopenia EWGSOP and osteoporosis in outpatient older adults. It is strong and significant in males; in females, despite showing a positive trend, it was not statistically significant.