2014 MERS-CoV Outbreak in Jeddah — A Link to Health Care Facilities

A substantial increase in Middle East respiratory syndrome coronavirus (MERS-CoV) infections in Saudi Arabia in 2014 raised concern about further spread of the disease. An investigation showed that health care–associated transmission was an important element in this outbreak. The Middle East respira...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 372; no. 9; pp. 846 - 854
Main Authors Oboho, Ikwo K, Tomczyk, Sara M, Al-Asmari, Ahmad M, Banjar, Ayman A, Al-Mugti, Hani, Aloraini, Muhannad S, Alkhaldi, Khulud Z, Almohammadi, Emad L, Alraddadi, Basem M, Gerber, Susan I, Swerdlow, David L, Watson, John T, Madani, Tariq A
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 26.02.2015
Subjects
Adult
Aged
Asymptomatic
Coronaviridae
Coronavirus Infections - epidemiology
Coronavirus Infections - transmission
Coronaviruses
Cross Infection - epidemiology
Disease Outbreaks
Disease transmission
Epidemiology
Female
Health facilities
Humans
Infection Control
Infections
Infectious Disease Transmission, Professional-to-Patient
Male
Middle Aged
Middle East Respiratory Syndrome Coronavirus
Outbreaks
Personnel
Respiratory diseases
Saudi Arabia - epidemiology
Zoonoses
Saudi Arabia
Jeddah Saudi Arabia
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Summary:A substantial increase in Middle East respiratory syndrome coronavirus (MERS-CoV) infections in Saudi Arabia in 2014 raised concern about further spread of the disease. An investigation showed that health care–associated transmission was an important element in this outbreak. The Middle East respiratory syndrome coronavirus (MERS-CoV), an emerging novel betacoronavirus belonging to lineage C, is known to cause severe acute respiratory illness in humans. From the time the disease was first identified in 2012, mortality among patients with laboratory-confirmed infection has been reported to be approximately 30 to 40%. 1 , 2 As of this writing, cases have been linked to seven countries in or near the Arabian Peninsula, and the majority of reported cases have been from Saudi Arabia. 3 , 4 A zoonotic origin of MERS-CoV has been presumed on the basis of evidence to date. The reservoir, mechanism of transmission, . . .
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Dr. Oboho and Ms. Tomczyk contributed equally to this article.
ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa1408636