Comparisons of short- and intermediate-term effects of pitavastatin versus atorvastatin on lipid profiles, fibrinolytic parameter, and endothelial function

• Published in: International journal of cardiology Vol. 125; no. 1; pp. 136 - 138
• Main Authors: Sakabe, Koichi, Fukuda, Nobuo, Fukuda, Yamato, Wakayama, Katsunori, Nada, Teru, Morishita, Satofumi, Shinohara, Hisanori, Tamura, Yoshiyuki
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 28.03.2008; Elsevier Science
• Subjects: Aged; Atorvastatin Calcium; Biological and medical sciences; Cardiology. Vascular system; Cardiovascular; Coronary Artery Disease - drug therapy; Coronary Artery Disease - physiopathology; Endothelial function; Endothelium, Vascular - drug effects; Female; Fibrinolysis - drug effects; Heptanoic Acids - pharmacology; Heptanoic Acids - therapeutic use; Humans; Hypercholesterolemia - drug therapy; Hypercholesterolemia - physiopathology; Hypolipidemic Agents - pharmacology; Lipid; Lipids - blood; Male; Medical sciences; Middle Aged; Pleiotropic effects; Prospective Studies; Pyrroles - pharmacology; Pyrroles - therapeutic use; Quinolines - pharmacology; Quinolines - therapeutic use; Statin; Time Factors; Vasodilation - drug effects; Statin; Endothelial function; Pleiotropic effects; Lipid; Short term; Lipids; Statin derivative; Phlebology; Profile; Pitavastatin; Atorvastatin; Parameter; Circulatory system; Cardiology; Comparative study; Fibrinolytic

Abstract We compared short- and intermediate-term effects on lipid profiles, fibrinolytic parameter, and endothelial function between pitavastatin and atorvastatin. Short-term improvement of endothelial function was superior with pitavastatin compared to atorvastatin therapy. Pitavastatin could be a...